Investigation of Canine Epilepsy
The purpose of this study is to utilize a very novel MRI technique known as SPectroscopic Imaging by exploiting spatiospectral CorElation (SPICE) to noninvasively measure brain metabolites in dogs with idiopathic epilepsy. SPICE is a form of magnetic resonance spectroscopy (MRS) that allows whole-brain measurement of brain metabolites. MRS has been used in people to allow the detection of the origin of the seizure activity within the brain as well as assisting with guiding therapeutic interventions, such as surgical intervention and potential responses to antiepileptic drugs (AEDs).
This study is fully funded for patients meeting all inclusion criteria.
See the trial announcement online for inclusion criteria, protocol, and other details or contact the Neurology & Neurosurgery Service at VTHNeurology@vetmed.illinois.edu or 217-300-6892.
Dogs with Cutaneous Lymphoma and Pruritus
Up to 88% of humans and up to 40% of dogs with CETL suffer from intense pruritus, which can cause significant morbidity and can affect quality of life. The purpose of this study is to measure serum IL-31 expression in dogs with cutaneous epitheliotropic T cell lymphoma (CETL) and evaluate its potential association with pruritus and disease severity. Also, to evaluate the use of Cytopoint, a monoclonal antibody against IL-31, as an antipruritic treatment for dogs with CETL and associated pruritus.
See the trial announcement online for inclusion criteria, protocol, and other details or contact the Dr. Souza at cpsouza@illinois.edu or 217-300-9446.
For details on these and other trials, see: vetmed.illinois.edu/research/clinical-trials/
