Research

Discovery at the College of Veterinary Medicine encompasses the spectrum of biomedical sciences.

The Office of Research and Advanced Studies serves a variety of functions:

• Serves as a resource to faculty and student researchers in the college;
• Administers the joint DVM/PhD Veterinary Medical Scholars Program;
• Administers the Summer Research Training Program for veterinary students;
• Oversees the college’s shared research equipment program;
• Administers the college’s internal research grants program;
• Organizes the annual Research Day program.

Research and graduate education occur within the three academic departments, listed below, with guidance and support from the Office of Research and Advanced Studies.

• Department of Comparative Biosciences
• Department of Pathobiology
• Department of Veterinary Clinical Medicine

To see the breadth of scholarly activity of college faculty, visit individual faculty biosketch pages or view the sampling of recent grants and publications below.

Selected Recent Grant Awards

SELECTED RECENT GRANT AWARDS

Genomic Imprinting in Circuits for Social Behavior
P Bonthuis; $249,000; National Institutes of Health

Great Ape Heart Disease: Harnessing the Power of Pathology to Improve the Clinical Care and Welfare of Ape Collections
K Terio; $253,583; Zoo Atlanta

Marek’s Disease Virus UL13 Virion Protein US10 and Cellular LY6E in Horizontal Transmission
K Jarosinski; $500,000; USDA NIFA

Functional Characterization of Novel Poxviral Immunomodulatory Proteins
D Rock; $500,000; USDA NIFA

Animal Disease Training and Exercises Across the Veterinary Educational Spectrum (AD-TEAVES)
Y Johnson-Walker; $429,835; USDA APHIS

A Multi-Audience Online Educational Program for Rural Practitioners and Veterinary Students Entering Rural Veterinary Practice
J Lowe; $236,750; USDA NIFA

Establish a Pregnant Sow Model for Assessment of Influenza Vaccine Safety and Efficacy During Pregnancy
Y Fang; $331,173; National Institutes of Health

Enhancing Undergraduate Research: Genome Data Mining and Laboratory Investigation to Reveal the Fungal Agglutinin-Like Sequence Family
L Hoyer; $475,800; National Institutes of Health

Maternal Control of Germ Line Development
J Yang; $823,151; National Institutes of Health

Risk Genes for Osteochrondrosis: An Integrated Approach
A McCoy; $149,906; Morris Animal Foundation

Characterization of the Fecal Microbiome in Dogs with Spinal Cord Injury Secondary to Intervertebral Disc Disease (IVDD)
K Foss; $14,958; American Kennel Club Canine Health Foundation

Detection of Elephant Endotheliotropic Herpesvirus (EEHV) 1A DNA using in situ Hybridization
J Landolfi; $12,150; International Elephant Foundation

Publications Recently Indexed in PubMed

Pressurized DNA state inside herpes capsids-A novel antiviral target.
Brandariz-Nuñez A, Robinson SJ, Evilevitch A. PLoS Pathog. 2020 Jul 23;16(7):e1008604. doi: 10.1371/journal.ppat.1008604. eCollection 2020 Jul. PMID: 32702029

Clinical features and outcome of functional thyroid tumours in 70 dogs.
Scharf VF, Oblak ML, Hoffman K, Skinner OT, Neal KM, Cocca CJ, Duffy DJ, Wallace ML. J Small Anim Pract. 2020 Jul 21. doi: 10.1111/jsap.13183. Online ahead of print. PMID: 32692404

Technical note: Evaluation of a colorimetric point-of-care test for measuring urine ammonium concentration in periparturient dairy cattle.
Megahed AA, Constable PD. J Dairy Sci. 2020 Jul 16:S0022-0302(20)30547-6. doi: 10.3168/jds.2020-18534. Online ahead of print. PMID: 32684458

Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies.
Heindel JJ, Belcher S, Flaws JA, Prins GS, Ho SM, Mao J, Patisaul HB, Ricke W, Rosenfeld CS, Soto AM, Vom Saal FS, Zoeller RT. Reprod Toxicol. 2020 Jul 12:S0890-6238(20)30150-7. doi: 10.1016/j.reprotox.2020.05.014. Online ahead of print. PMID: 32682780 Free PMC article.

Autophagy core protein ATG5 is required for elongating spermatid development, sperm individualization and normal fertility in male mice.
Huang Q, Liu Y, Zhang S, Yap YT, Li W, Zhang D, Gardner A, Zhang L, Song S, Hess RA, Zhang Z. Autophagy. 2020 Jul 17:1-15. doi: 10.1080/15548627.2020.1783822. Online ahead of print. PMID: 32677505

The protein YWHAE (14-3-3 epsilon) in sperm is essential for male fertility.
Eisa A, Dey S, Ignatious A, Nofal W, Hess RA, Kurokawa M, Kline D, Vijayaraghavan S. Andrology. 2020 Jul 13. doi: 10.1111/andr.12865. Online ahead of print. PMID: 32657535

Origin and main ramifications of celiac artery in Cerdocyon thous.
Viana-Peçanha S, Souza EC, Guerra DML, Bernardes FCS, Carvalho RBJ, de Souza Junior P, Abidu-Figueiredo M. Folia Morphol (Warsz). 2020 Jul 9. doi: 10.5603/FM.a2020.0072. Online ahead of print. PMID: 32644185 Free article.

Management of a severe peripartum hemorrhage following cesarean section in a dog.
Doodnaught GM, O’Toole E, Pang DSJ. Can Vet J. 2020 Jun;61(6):589-594. PMID: 32675810

Risk factor analysis of bovine leukemia virus infection in dairy cattle in Egypt.
Selim A, Megahed AA, Kandeel S, Abdelhady A. Comp Immunol Microbiol Infect Dis. 2020 Jul 8;72:101517. doi: 10.1016/j.cimid.2020.101517. Online ahead of print. PMID: 32682151

Implementation of permeation rules leads to a FabI inhibitor with activity against Gram-negative pathogens.
Parker EN, Drown BS, Geddes EJ, Lee HY, Ismail N, Lau GW, Hergenrother PJ. Nat Microbiol. 2020 Jan;5(1):67-75. doi: 10.1038/s41564-019-0604-5. Epub 2019 Nov 18. PMID: 31740764 Free PMC article.

The potential of retinoids for combination therapy of lung cancer: Updates and future directions.
Tripathi SK, Pandey K, Panda M, Spinella MJ, Rengasamy KR, Biswal BK. Pharmacol Res. 2019 Sep;147:104331. doi: 10.1016/j.phrs.2019.104331. Epub 2019 Jun 26. PMID: 31254665 Free PMC article. Review.

Vaccines against gastroenteritis, current progress and challenges.
Seo H, Duan Q, Zhang W. Gut Microbes. 2020 Nov 1;11(6):1486-1517. doi: 10.1080/19490976.2020.1770666. Epub 2020 Jun 18. PMID: 32552414

A porcine macrophage cell line that supports high levels of replication of OURT88/3, an attenuated strain of African swine fever virus.
Portugal R, Goatley LC, Husmann R, Zuckermann FA, Dixon LK. Emerg Microbes Infect. 2020 Dec;9(1):1245-1253. doi: 10.1080/22221751.2020.1772675. PMID: 32515659 Free article.