Research

Discovery at the College of Veterinary Medicine encompasses the spectrum of biomedical sciences.

The Office of Research and Advanced Studies serves a variety of functions:

• Serves as a resource to faculty and student researchers in the college;
• Administers the joint DVM/PhD Veterinary Medical Scholars Program;
• Administers the Summer Research Training Program for veterinary students;
• Oversees the college’s shared research equipment program;
• Administers the college’s internal research grants program;
• Organizes the annual Research Day program.

Research and graduate education occur within the three academic departments, listed below, with guidance and support from the Office of Research and Advanced Studies.

• Department of Comparative Biosciences
• Department of Pathobiology
• Department of Veterinary Clinical Medicine

To see the breadth of scholarly activity of college faculty, visit individual faculty biosketch pages or view the sampling of recent grants and publications below.

Selected Recent Grant Awards

SELECTED RECENT GRANT AWARDS

Phthalates and Ovarian Toxicity
J Flaws; $1,961,209; National Institutes of Health

The Role of Lpcat3 and Phospholipid Remodeling in Intestinal Homeostasis
B Wang; $660,020; National Institutes of Health

Ultraviolet Fluorescence of Lake Erie Watersnakes (Nerodia sipedon insularum) as a Non-Invasive Diagnostic Tool for Ophidiomycosis (Ophidiomyces ophiodiicola)
M Allender, K Vivirito; $5,000; Morris Animal Foundation Veterinary Scholars Program

Role of Glycine Decarboxylase in Regulating NMDA Receptor Function
U Rudolph; $699,988; National Institutes of Health

Evidence-Based Strategies to Improve Feedback in Teaching
L Garrett; $900; American Veterinary Medical Association Veterinary Educator Grant

Synovial Ossification in Osteoarthritis: Mechanisms and Therapeutic Targeting
M Stewart; $29,850; Veterinary Orthopedic Society

Validation of Fine Needle Aspiration as a Minimally Invasive Sampling Method for Gene Expression Quantification of Pharmacogenetic Targets
J Reinhart, M Vieson; $5,979; American Kennel Club

Maddie’s Shelter Medicine Internship at the University of Illinois College of Veterinary Medicine
D-L Agapis; $47,118; Maddie’s Fund

Anti-Inflammatory Endocannabinoids as Potential MS Therapeutics
A Das; $55,000; National Multiple Sclerosis Society

Synergizing Radiation-Induced Immunogenic Cell Death and Toll-like Receptor 9 Agonism to Generate Abscopal Effects in Canine Osteosarcoma
T Fan; $194,555; Morris Animal Foundation

Publications Recently Indexed in PubMed

Comparative study on the efficacy of sodium hypochlorite, aqueous ozone, and peracetic acid in the elimination of Salmonella from cattle manure contaminated various surfaces supported by Bayesian analysis.
Megahed A, Aldridge B, Lowe J. PLoS One. 2019 May 23;14(5):e0217428. doi: 10.1371/journal.pone.0217428. eCollection 2019. PMID: 31120988

DETECTION OF MYCOPLASMA SP. IN INDOCHINESE BOX TURTLES (CUORA BOURRETI).
DiGeronimo PM, Hansen C, Latney LV, Adamovicz LA, Allender MC. J Zoo Wildl Med. 2019 Apr;50(1):254-257. doi: 10.1638/2018-0091. PMID: 31120686

EFFECTS OF OXYGEN AND ISOFLURANE ANESTHESIA ON HEMOLYMPH GAS ANALYSIS AND RIGHTING REFLEX OF ASIAN FOREST (HETEROMETRUS LONGIMANUS) AND DICTATOR SCORPIONS (PANDINUS DICTATOR).
Sheldon JD, Adamovicz L, Burvenich P, Chinnadurai SK, Allender MC. J Zoo Wildl Med. 2019 Apr;50(1):111-122. doi: 10.1638/2018-0173. PMID: 31120669

TISSUE ENZYME ACTIVITIES IN FREE-LIVING EASTERN BOX TURTLES (TERRAPENE CAROLINA CAROLINA).
Adamovicz L, Griffioen J, Cerreta A, Lewbart GA, Allender MC. J Zoo Wildl Med. 2019 Apr;50(1):45-54. doi: 10.1638/2018-0079. PMID: 31120661

Engineering a live attenuated PEDV vaccine candidate via inactivation of the viral 2′-O methyltransferase and the endocytosis signal of the spike protein.
Hou Y, Ke H, Kim J, Yoo D, Su Y, Boley P, Chepngeno J, Vlasova AN, Saif LJ, Wang Q. J Virol. 2019 May 22. pii: JVI.00406-19. doi: 10.1128/JVI.00406-19. [Epub ahead of print] PMID: 31118255

Comparison of the Sedative Effects of Alfaxalone and Butorphanol-Midazolam Administered Intramuscularly in Budgerigars (Melopsittacus undulatus).
Escalante GC, Balko JA, Chinnadurai SK. J Avian Med Surg. 2018 Dec;32(4):279-285. doi: 10.1647/2017-328. PMID: 31112640

Diagnostic Performance of Clinicopathological Analytes in Otostrongylus circumlitis-Infected Rehabilitating Juvenile Northern Elephant Seals (Mirounga angustirostris).
Sheldon JD, Hernandez JA, Johnson SP, Field C, Kaye S, Stacy NI. Front Vet Sci. 2019 Apr 25;6:134. doi: 10.3389/fvets.2019.00134. eCollection 2019. PMID: 31106217

Agglutinin-Like Sequence (ALS) Genes in the Candida parapsilosis Species Complex: Blurring the Boundaries Between Gene Families That Encode Cell-Wall Proteins.
Oh SH, Smith B, Miller AN, Staker B, Fields C, Hernandez A, Hoyer LL. Front Microbiol. 2019 Apr 26;10:781. doi: 10.3389/fmicb.2019.00781. eCollection 2019. PMID: 31105652

Contribution of the Mucosal Microbiota to Bovine Respiratory Health.
Zeineldin M, Lowe J, Aldridge B. Trends Microbiol. 2019 May 16. pii: S0966-842X(19)30098-8. doi: 10.1016/j.tim.2019.04.005. [Epub ahead of print] Review. PMID: 31104970

Emerging Class of Omega-3 Fatty Acid Endocannabinoids & Their Derivatives.
Watson JE, Kim JS, Das A. Prostaglandins Other Lipid Mediat. 2019 May 11:106337. doi: 10.1016/j.prostaglandins.2019.106337. [Epub ahead of print] Review. PMID: 31085370

The epigenetic impacts of endocrine disruptors on female reproduction across generations†.
Rattan S, Flaws JA. Biol Reprod. 2019 May 11. pii: ioz081. doi: 10.1093/biolre/ioz081. [Epub ahead of print] PMID: 31077281