Professional Profile

image for Hoyer, Lois L

Hoyer, Lois L

Professor of Pathobiology
College of Veterinary Medicine
2001 South Lincoln Avenue
2211 Vet Med Basic Sciences Bldg
Urbana, IL  61802

Research Interests

My research interests focus on studies of pathogenic fungi, particularly Candida albicans.


show listGrants

  • Enhancing Undergraduate Research: Genome Data Mining and Laboratory Experimentation to Reveal the Fungal Agglutinin-Like Sequence Family, National Institute of Dental and Craniofacial Research, R15 DE026401. (Role: PI).
  • Summer Training in Translational Biomedical Research, Office of the Director, National Institutes of Health, T35 OD011145. (Role: PI).

show listSelected Publications

  • Oh, S.-H., K. Schliep, A. Isenhower, R. Rodriguez-Bobadilla, V.M. Vuong, C.J. Fields, A.G. Hernandez and L.L. Hoyer. 2021. Using genomics to shape the definition of the agglutinin-like sequence (ALS) family in the Saccharomycetales. Frontiers in Cellular and Infection Microbiology 11:794529. doi:10.3389/fcimb.2021.794529.
  • Elwart, O.E., J.B. Pieper, S.-H. Oh, T.E. Wilcoxen and L.L. Hoyer. 2021. Effect of light exposure on growth rate of veterinary clinical dermatophyte isolates. Veterinary Dermatology 32:234-e61. doi:10.1111/vde.12945.
  • Oh, S.-H., B. Smith, A.N. Miller, B. Staker, C. Fields, A. Hernandez and L.L. Hoyer. 2019. Agglutinin-like sequence (ALS) genes in the Candida parapsilosis species complex: blurring the boundaries between gene families that encode cell-wall proteins. Frontiers in Microbiology 10:781. doi:10.3389/fmicb.2019.00781.
  • Hoyer, L.L. and E. Cota. 2016. Candida albicans agglutinin-like sequence (Als) family vignettes: a review of Als protein structure and function. Frontiers in Microbiology 7:208. doi:10.3389/fmicb.2016.00280.
  • Cota, E. and L.L. Hoyer. 2015. The Candida albicans agglutinin-like sequence family of adhesins: functional insights gained from structural analysis. Future Microbiology 10:1635-1648. doi:10:2217/fmb.15.79.
  • Hoyer, L.L., S.-H. Oh, R. Jones and E. Cota. 2014. A proposed mechanism for the interaction between the Candida albicans Als3 adhesin and streptococcal cell wall proteins. Frontiers in Microbiology 5:564. doi:10.3389/fmicb.2014.00564.
  • Hoeflinger, J., D.A. Coleman, S.-H. Oh, M.J. Miller and L.L. Hoyer. 2014. A piglet model for studying Candida albicans colonization of the human oro-gastrointestinal tract. FEMS Microbiology Letters 357:10-15. doi:10.1111/1574-6968.12500.
  • Lin, J., S.-H. Oh, R. Jones, J.A. Garnett, P.S. Salgado, S. Rusnakova, S. Matthews, L.L. Hoyer and E. Cota. 2014. The peptide-binding cavity is essential for Als3-mediated adhesion of Candida albicans to human cells. Journal of Biological Chemistry 289:18401-18412, doi:10.1074/jbc.M114.547877.
  • Sieklucki, U., S.-H. Oh and L.L. Hoyer. 2014. Frequent isolation of Arthroderma benhamiae from dogs with dermatophytosis. Veterinary Dermatology 25:39-e14. doi:10.1111/vde.12095.
  • Coleman, D.A., S.-H. Oh, S.L. Manfra-Maretta, and L.L. Hoyer. 2012. A monoclonal antibody specific for Candida albicans Als4 demonstrates overlapping localization of Als family proteins on the fungal cell surface and highlights differences between Als localization in vitro and in vivo. FEMS Immunology and Medical Microbiology 64:321-333. doi:10.1111/j.1574-695X.2011.00914.x.
  • Salgado, P.S., R. Yan, J.D. Taylor, L. Burchell, R. Jones, L.L. Hoyer, S.J. Mathews, P.J. Simpson and E. Cota. 2011. Structural basis for the broad specificity to host-cell ligands by the pathogenic fungus Candida albicans. Proceedings of the National Academy of Sciences USA 108:15775-15779. doi:10.1073/pnas.1103496108.
  • Coleman, DA, S.-H. Oh, X. Zhao, and L.L. Hoyer. 2010. Heterogeneous distribution of Candida albicans cell-surface antigens demonstrated with an Als1-specific monoclonal antibody. Microbiology 156:3645-3659. doi:10.1099/mic.0.043851-0.
  • Butler, G., M.D. Rasmussen, M.F. Lin, et al. 2009. Evolution of pathogenicity and sexual reproduction in eight Candida genomes. Nature 459:657-662. doi:10.1038/nature08064.

show listCourses Taught

  • VM 607, Pathobiology II (Mycology unit)
  • PATH 190, Discovery Course, Journeys into the Microbial World
  • PATH 513, Biomedical Grant Proposal Writing
  • PATH 644, Bioscientific Writing
  • Summer Research Training Program for Veterinary Students
  • VM 622, Research Project I
  • VM 623, Research Project II