* denotes corresponding author or first author
2017
37. Maroutsos, D., Huff, H., and Das, A*, "N-terminal modification to increase expression of Eukaryotic P450s in E.Coli - CYP5alpha Hydroxylase and CYP2J2 epoxygenase" Methods in Molecular Biology, Book Chapter. Submitted
36. McDougle, D.R., Abdeen,A., Adili, R., Caputo, M., Krapf, J., Johnson, R., Kilian, K., Holinstat, M., Das, A*, "Anti-inflammatory Omega-3 Endocannabinoid Epoxides", PNAS (Direct Submission), Accepted with Minor Revisions
35. Roy, J. Pondenis, H., Fan T.*, Das, A*, "Comparative Proteomic Analysis of Metastatic and Non-metastatic Osteosarcoma of Human and Canine Origin" PLOS One, Accepted with Minor Revisions
32. Rouck*, J.E., Bradley*, WB.,Kambalyal, A.,Parayil, A*. and Das, A*., "Expression and Purification of cytochrome P450 taxadiene 5alpha-hydroxylase in E.Coli", Protein Expression and Purification, Protein Expr Purif. 2017 Jan 18;132:60-67. doi: 10.1016/j.pep.2017.01.008.
2016
33. Arnold, W., Baylon, J, Tajkorshid, E.* and Das, A.*,"Docosahexaenoic acid (DHA) preferentially binds to cardiovascular CYP2J2 and inhibits arachidonic acid (AA) metabolism" Biochemistry. 2016, 55(50):6969-6980
32. Biochemistry, 2015, 54 (41), pp 6299–6302. Plucinski, L., Gartia, M., Arnold, W., Ameen, A., Chang, T., Hsiao, A., Liu, G.*, Das, A.*, "Substrate Binding to CYP2J2- Nanodiscs Detected by Nanoplasmonic Lygurcus Cup Arrays" Biosens Bioelectron., 2016, 337-46.
31. Lim, SJ, McDougle, D., Das, A* and Smith, A.*, "Lipoprotein Nanoplatelets: Fluorescent, Zwitterionic Probes for Molecular and Cellular Imaging." Journal of the American Chemical Society, 2016 ASAP.
30. Roy, J. Pondenis, H., Fan T.*, Das, A*, "Direct Capture of Functional Proteins from Mammalian Plasma Membranes into Nanodiscs" Biochemistry, 2015, 6299–6302.
29. McDougle, D*., Baylon, J.* Meling D., Kambalyal, A., Tajkorshid, E.*, and Das, A* "Incorporation of Charged Residues in the CYP2J2 F-G Loop Disrupts CYP2J2-Lipid Bilayer Interactions" Biochimica et Biophysica Acta -Biomembranes, 2015, 2060-2470.
28. Zelasko, S, Meling, D. and Das A*. "A critical residue that controls the isomerization of prostaglandin in thromboxane synthase", Biophysical Chemistry, 2015, 34-40.
27. Wilcox, K., Das, A., Velasco, P., Sligar S.G. and Klein, W. "Nanoscale synaptic membrane mimetic allows unbiased high throughput screen that targets binding sites for Alzheimer’s-associated Aβ oligomers" 2015, PLOS ONE In Press
26. Zelasko, S., Arnold, W., Das, A* " Endocannabinoid Metabolism by Cytochrome P450 Monooxygenases.", Prostaglandins and Other Lipid Mediators. 2015, http://www.sciencedirect.com/science/article/pii/S1098882314000744
(News: Most downloaded article is at POLM)
2014
25. McDougle, D., Kambalayal, A., Meling, D. and Das, A*. "Endocannabinoids - Anandamide and 2- Arachidonoylglycerol are Substrates for Human CYP2J2 Epoxygenase" Journal of Pharmacology and Experimental Therapeutics, 2014, 616-27.
24. Meling, D., McDougle, D. and Das, A.*,"CYP2J2 epoxygenase membrane anchor plays an important role in facilitating electron transfer from CPR." Journal of Inorganic Biochemistry 2014, 47-53.
23. Orlando, B., McDougle, D., Lucido, M., Eng, E., Stokes, D., Das, A*., and Malkowski, M*. "Cyclooxygenase-2 Catalysis and Inhibition in Lipid Bilayer Nanodiscs" Archives of Biochemistry and Biophysics 2014, 546, 33-40.
22. Srivarma, S., Mularcyzk, C. Meling, D. and Das, A*. "Substrate binding thermodynamics and kinetics to thromboxane synthase in model lipid bilayers", ChemBioChem. 2014, 15, 892
2013
21. Zelasko S., Palaria, A., and Das, A* "Modifications to produce high-level expression of mammalian cytochrome P450s in recombinant expression systems" Protein Expression and Purification,2013,92,77-87
20. McDougle, D*., Palaria, A.*Magnetta E., Meling, D. and Das, A*. "Functional Studies of N-terminally modified CYP2J2 epoxygenase in Model Lipid Bilayers", Protein Science, 2013, 22,964 (Amrita Palaria and Daniel McDougle are equal authors)
19. Marty, M., Das, A., Sligar, S.G. “MALDI Mass Spectrometry of Membrane Proteins in Nanodiscs”, Analytical Bioanalytical Chemistry, 2012, Accepted.
18. Das, A., Wei, Y., Pelczer, I. and Hecht, M.H. “Binding of Small Molecules to Cavity Forming Mutants of a De Novo Designed Protein”, Protein Science, 2011, 20, 702–711.
(In News) Editor Highlight in Protein Science
17. Turk, S., Das, A., Sligar, S. G. and Dravid, V. “Nanomechanical Detection of Cholera Toxin Using Microcantilevers Functionalized with Ganglioside-Nanodiscs” Nanotechnology, 2010, 21, 435502.
(In News): Nanomechanical sensor can detect cholera. Nanowerk Spotlight
15. Das. A., Zhao, J. Van Duyne, R. and Sligar, S.G. “Screening of Type I and II Drug Binding to Human Cytochrome P450-3A4 in Nanodiscs by Localized Surface Plasmon Resonance Spectroscopy”,Anal. Chem., 2009, 81 (10), 3754–3759.
14. Li, H., Das, A., Sibhatu, H., Jamal, J., Sligar, S. and Poulos, T.L. “Exploring the Electron Transfer Properties of Neuronal Nitric Oxide Synthase by Reversal of the FMN Redox Potential” J. Biol. Chem. 2008, 283 (50), 34762-34772.
12. Gruia,F., Ionascu,D. , Kubo, M. Ye, X., Dawson, J., Osborne, R.L., Sligar, S. G., Denisov, I., Das, A. Poulos, T. L., Terner, J. and Champion, P.M. “Low Frequency Dynamics of Caldariomyces fumagoChloroperoxidase Probed by Femtosecond Coherence Spectroscopy” Biochemistry 2008, 47(18), 5156-5167.
11. Das. A., Grinkova, Y. and Sligar, S.G. “Redox Potential Control by Drug Binding to Cytochrome P450 3A4.” J. Am. Chem. Soc. 2007, 129 (45), 13778-13779
9. Kimmich, N., Das. A., Sevrioukova, I, Meharenna, Y., Sligar, S.G. and Poulos, T. L. “Electron Transfer between P450cin and its FMN-Containing Redox Partner” J. Biol. Chem., 2007, 282 (37), 27006-27011
8. Zhao*, J., Das, A.*, Zhang, X, Schatz, G., Sligar, S., Van Duyne, R. “Resonance Surface Plasmon Spectroscopy: Low Molecular Weight Substrate Binding to Cytochrome P450” J. Am. Chem. Soc. 2006, 128 (34), 11004-11005. (* Co-first authors)
(In News): (1) Enhanced LSPR detects binding of small molecules. Anal. Chem., 2006, 78(21), 7356. (2) Kirrill’s Café paper of the month. August 2006
5. Hecht, M.H., Das, A., Go, A., Bradley, L. and Wei, Y. (2004) “De Novo Proteins from Designed Combinatorial Libraries.” Protein Science 2004, 13(7), 1711–1723.
4. Das, A. “Electrochemical and Functional Studies of De Novo Alpha Helical Protein from a Designed Combinatorial Library.” Ph.D Thesis Princeton University November 2005
3. Das, A. Model Chemistry of Aerobic Acetylene Hydratase Enzymes. M.Sc. Thesis: I.I.T (Kanpur) 1998
