Research


We study life forms from bacteria and fungi to humans and animals, as individuals and populations. Our research draws on disciplines from cell and molecular biology to epidemiology, applied medicine, and geospatial analysis.

[Dr. Edward adn Mrs. Virginia Voss]
[Peter D. Constable and a calf]
medical college faculty
[petri dish used to grow fungus]
[snake with fungal disease]
[vector-borne disease Culex larvae]
turtle

Discovery at the College of Veterinary Medicine encompasses the spectrum of biomedical sciences.

The Office of Research and Advanced Studies serves a variety of functions:

Research and graduate education occur within the three academic departments, listed below, with guidance and support from the Office of Research and Advanced Studies.

To see the breadth of scholarly activity of college faculty, visit individual faculty biosketch pages or view the sampling of recent grants and publications below.

 

Selected Recent Grant Awards

Summer Undergraduate Research Experience in Toxicology.

Flaws, J, $54,120, National Institutes of Health.

Carboplatin-Impregnated Calcium Sulfate Hemihydrate Beads: a Cost-Effective, Local Treatment for Feline Injection Site-Associated Sarcoma.

Maxwell, E, $11,383, American College of Veterinary Surgeons.

Nannizziopsiaceae sp. Infection in Aquatic Chelonians.

Terio K and Woodburn D, $100,000, Morris Animal Foundation.

Enhancing Undergraduate Research: Genome Data Mining to Define the Fungal Agglutinin-Like Sequence Family.

Hoyer L, $475,800, National Institutes of Health.

Using Optical Coherence Tomography for Margin Evaluation of Canine Mammary Tumors and Soft Tissue Sarcomas.

Selmic L, $46,358, American Kennel Club.

Biomechanical and Genetic Risk Factors for Osteochondrosis in Standardbred Pacers and Trotters.

McCoy A, $81,305, Morris Animal Foundation.

Sterilization of 1,000 Feral and Free-Roaming Cats While Training Fourth-Year Veterinary Students.

Weedon GR, $29,950, American Society for the Prevention of Cruelty to Animals.

Biomechanical Comparison of Equine Arytenoid Cartilage Stabilization by Standard Laryngoplasty and Modified Laryngoplasty Using a Toggle Technique.

Gutierrez-Nibeyro S, $4,860, Morris Animal Foundation.

Biochemical Mechanism of CYP2J2 Epoxygenase.

Das A, $308,000, American Heart Association.


Recent Publications

G0S2 represses PI3K/mTOR signaling and increases sensitivity to PI3K/mTOR pathway inhibitors in breast cancer.
Yim CY, Bikorimana E, Khan E, Warzecha JM, Shin L, Rodriguez J, Dmitrovsky E, Freemantle SJ, Spinella MJ. Cell Cycle. 2017 Sep 14:1-10. doi: 10.1080/15384101.2017.1371884. [Epub ahead of print] PMID: 28910567

Anesthetic effects and body weight changes associated with ketamine-xylazine-lidocaine administered to CD-1 mice.
Dholakia U, Clark-Price SC, Keating SCJ, Stern AW. PLoS One. 2017 Sep 14;12(9):e0184911. doi: 10.1371/journal.pone.0184911. eCollection 2017. PMID: 28910423

Comparative proteomic investigation of metastatic and non-metastatic osteosarcoma cells of human and canine origin.
Roy J, Wycislo KL, Pondenis H, Fan TM, Das A. PLoS One. 2017 Sep 14;12(9):e0183930. doi: 10.1371/journal.pone.0183930. eCollection 2017. PMID: 28910304

Immunogenicity of ORFV-based vectors expressing the rabies virus glycoprotein in livestock species.
Martins M, Joshi LR, Rodrigues FS, Anziliero D, Frandoloso R, Kutish GF, Rock DL, Weiblen R, Flores EF, Diel DG. Virology. 2017 Sep 9;511:229-239. doi: 10.1016/j.virol.2017.08.027. [Epub ahead of print] PMID: 28898730

Rabacfosadine for relapsed canine B-cell lymphoma: Efficacy and adverse event profiles of 2 different doses.
Saba CF, Vickery KR, Clifford CA, Burgess KE, Phillips B, Vail DM, Wright ZM, Morges MA, Fan TM, Thamm DH. Vet Comp Oncol. 2017 Sep 11. doi: 10.1111/vco.12337. [Epub ahead of print] PMID: 28891260

Effect of feeding on the pharmacokinetics of oral minocycline in healthy adult horses.
Echeverria KO, Lascola KM, Giguère S, Foreman JH. J Vet Pharmacol Ther. 2017 Sep 11. doi: 10.1111/jvp.12456. [Epub ahead of print] PMID: 28891075

Disparity in the nasopharyngeal microbiota between healthy cattle on feed, at entry processing and with respiratory disease.
Zeineldin M, Lowe J, de Godoy M, Maradiaga N, Ramirez C, Ghanem M, Abd El-Raof Y, Aldridge B. Vet Microbiol. 2017 Sep;208:30-37. doi: 10.1016/j.vetmic.2017.07.006. Epub 2017 Jul 13. PMID: 28888646

Effects of profound acidemia on the dynamic glucose and insulin response and plasma potassium and phosphorus concentrations during an intravenous glucose tolerance test in neonatal calves.
Trefz FM, Lorenz I, Constable PD. J Dairy Sci. 2017 Sep 6. pii: S0022-0302(17)30824-X. doi: 10.3168/jds.2017-12690. [Epub ahead of print] PMID: 28888605

Effects of topical flurbiprofen sodium, diclofenac sodium, ketorolac tromethamine and benzalkonium chloride on corneal sensitivity in normal dogs.
Cantarella RA, de Oliveira JK, Dorbandt DM, Montiani-Ferreira F. Open Vet J. 2017;7(3):254-260. doi: 10.4314/ovj.v7i3.9. Epub 2017 Aug 24. PMID: 28884078

INNOPLANT Total Hip Replacement System.
Harper TAM. Vet Clin North Am Small Anim Pract. 2017 Jul;47(4):935-944. doi: 10.1016/j.cvsm.2017.03.003. Review. PMID: 28576275

Femoral Head and Neck Excision.
Harper TAM. Vet Clin North Am Small Anim Pract. 2017 Jul;47(4):885-897. doi: 10.1016/j.cvsm.2017.03.002. Review. PMID: 28576273

Conservative Management of Hip Dysplasia.
Harper TAM. Vet Clin North Am Small Anim Pract. 2017 Jul;47(4):807-821. doi: 10.1016/j.cvsm.2017.02.007. Review. PMID: 28576270

Canine Hip Dysplasia Screening Within the United States: Pennsylvania Hip Improvement Program and Orthopedic Foundation for Animals Hip/Elbow Database.
Reagan JK. Vet Clin North Am Small Anim Pract. 2017 Jul;47(4):795-805. doi: 10.1016/j.cvsm.2017.02.003. Epub 2017 Apr 21. Review. PMID: 28434528