Professional Profile

image for Won, Taejoon

Won, Taejoon

Assistant Professor
2001 South Lincoln Ave.
2001 S Lincoln
M/C 002
Urbana, IL  61802

show listEducation

  • Ph.D. in Immunology, Laboratory of Host Defense Modulation, College of Pharmacy, Chung-Ang University, Seoul, South Korea (Advisor: Kwang Woo Hwang, Ph.D. and Do-Ik Lee, Ph.D.)
  • M.S. in Immunology, Department of Immunology, College of Pharmacy, Chung-Ang University, Seoul, South Korea (Advisor: Do-Ik Lee, Ph.D.)
  • B.S. in Pharmacy, College of Pharmacy, Chung-Ang University, Seoul, South Korea

show listAcademic Positions

  • Assistant Professor, Department of Pathobiology, College of Veterinary Medicine, University of Illinois Urbana-Champaign, Urbana, IL
  • Postdoctoral Fellow, Division of Immunology, Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD (Mentor: Daniela Čiháková, M.D., Ph.D.)
  • Postdoctoral Fellow, Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI (Mentor: Yasmina Laouar, Ph.D.)

show listResearch Interests

The heart is special. When it gets sick, it can jeopardize our overall well-being. When it stops functioning, our lives come to an end. Our lab is dedicated to the study of the immune system in the heart, with the aim of protecting it against inflammatory diseases. Inflammation in the heart due to microbial infections, autoimmune responses, or medications can lead to severe heart failure conditions. Our lab's primary goal is to develop innovative approaches for diagnosing, treating, and ultimately preventing inflammatory heart diseases.

show listHonors and Awards

  • The Outstanding Abstract in Clinical Research, 25th Annual Department of Pathology Young Investigators’ Day, Johns Hopkins University School of Medicine, 2023
  • Grover M. Hutchins, M.D. Memorial Research Award, Department of Pathology, Johns Hopkins University School of Medicine, 2022
  • Excellence in Clinical Research, 24th Annual Department of Pathology Young Investigator’s Day, Johns Hopkins University School of Medicine, 2022
  • American Association of Immunologists (AAI) Trainee Abstract Award, Virtual Immunology 2021, AAI, 2021
  • Excellence in Basic Research, 22ndAnnual Department of Pathology Young Investigators’ Day, Johns Hopkins University School of Medicine, 2020
  • Rhett Lundy Memorial Research Fellowship Grant, Myocarditis Foundation, 2019

show listSelected Publications

  • Jo W, Won T*, Daoud A, Čiháková D. Immune checkpoint inhibitors associated cardiovascular immune-related adverse events. Front Immunol. 2024 Feb 5;15:1340373.
  • Wood MK, Daoud A, Talor MV, Kalinoski HM, Hughes DM, Hooper JE, Won T#, Čiháková D. PD-L1-expressing macrophages play a protective role in the joint during arthritis. Arthritis Rheumatol. 2023 Nov 24. Online ahead of print.
  • Diny NL, Wood MK, Won T, Talor MV, Lukban C, Bedja D, Wang N, Kalinoski H, Daoud A, Talbot CC Jr, Leei Lin B, Čiháková D. Hypereosinophilia causes progressive cardiac pathologies in mice. iScience. 2023 Oct 20;26(10):107990.
  • Daoud A, Lema DA, Won T, Čiháková D. Integrative single-cell analysis of cardiac and pulmonary sarcoidosis using publicly available cardiac and bronchoalveolar lavage fluid sequencing datasets. Front Cardiovasc Med. 2023 Jul 28;10:1227818.
  • Won T, Kalinoski HM, Wood MK, Hughes DM, Jaime CM, Talor MV, Lasrado N, Reddy J, Čiháková D. Cardiac myosin-specific autoimmune T cells contribute to immune checkpoint inhibitor-associated myocarditis. Cell Rep. 2022;41(6):111611.
  • Won T*, Gilotra NA, Wood MK, Hughes DM, Talor MV, Lovell J, Milstone AM, Steenbergen C, Čiháková D. Increased interleukin 18-dependent immune responses are associated with myopericarditis after COVID-19 mRNA vaccination. Front Immunol. 2022;13:851620.
  • Won T, Wood MK, Hughes DM, Talor MV, Ma Z, Schneider J, Skinner JT, Asady B, Goerlich E, Halushka MK, Hays AG, Kim DH, Parikh CR, Rosenberg AZ, Coppens I, Johns RA, Gilotra NA, Hooper JE, Pekosz A, Čiháková D. Endothelial thrombomodulin downregulation caused by hypoxia contributes to severe infiltration and coagulopathy in COVID-19 patient lungs. EBioMedicine. 2022;75:103812.
  • Bracamonte-Baran W, Gilotra NA, Won T, Rodriguez KM, Talor MV, Oh BC, Griffin J, Wittstein I, Sharma K, Skinner J, Johns RA, Russell SD, Anders RA, Zhu Q, Halushka MK, Brandacher G, Čiháková D. Endothelial Stromal PD-L1 (Programmed Death Ligand 1) Modulates CD8+ T-Cell Infiltration After Heart Transplantation. Circ Heart Fail. 2021;14(10):e007982.
  • Choi HS, Won T, Hou X, Chen G, Bracamonte-Baran W, Talor MV, Jurčová I, Szárszoi O, Stříž  I, Hooper J, Melenovský V, Čiháková D. Innate Lymphoid Cells Play an Essential Role in pericarditis. Cell Rep. 2020;30(9):2989-3003.
  • Hou X, Chen G, Bracamonte-Baran W, Choi HS, Diny NL, Sung J, Hughes D, Won T, Wood MK, Talor MV, Hackam DJ, Klingel K, Davogustto G, Taegtmeyer H, Coppens I, Barin JG, Čiháková D. The Cardiac Microenvironment Instructs Divergent Monocyte Fates and Functions in Myocarditis. Cell Rep. 2019;28(1):172-189.

#Co-corresponding author; *Co-first author

show listLinks

show listRecent Press

show listPatents

  • Novel lactobacillus plantarum and composition comprising same. US20210069270A1 (pending). Kim BJ, Jung HW, Hwang SE, Lee JH, Lee KP, Hwang KW, Won TJ.
  • Novel lactobacillus plantarum and composition comprising the same. US20210054467A1 (pending). Kim BJ. Jung HW, Lee KP, Kim SH, Chun TH, Hwang KW, Won TJ.
  • Lactobacillus plantarum and composition comprising same. US10842833B2 (November 24, 2020). Kim BJ, Jung HW, Hwang SH, Lee JH, Lee KP, Hwang KW, Won TJ
  • Lactobacillus plantarum and composition comprising the same. US10844443B2 (November 24, 2020). Kim BJ, Jung HW, Lee KP, Kim SH, Chun TH, Hwang KW, Won TJ.
  • Lactobacillus plantarum and composition comprising same. US10130666B2 (November 20, 2018). Kim BJ, Jung HW, Hwang SH, Lee JH, Lee KP, Hwang KW, Won TJ.
  • Lactobacillus plantarum and composition comprising the same. US10093995B2 (October 9, 2018). Kim BJ, Jung HW, Lee KP, Kim SH, Chun TH, Hwang KW, Won TJ.
  • Lactobacillus plantarum and composition containing same. US9962417B2 (May 8, 2018). Kim BJ, Jung HW, Koh JH, Kim TJ, Lee KP, Hwang KW, Won TJ.
  • Lactobacillus plantarum and composition containing same. US9572846B2 (February 21, 2017). Kim BJ, Jung HW, Koh JH, Kim TJ, Lee KP, Hwang KW, Won TJ.
  • Food composition for preventing and improving of metabolic bone disease comprising extract of Sophorae fructus. KR100510426B1 (August 26, 2005). Kwon SH, Hwang BS, Kim KH, Lee SH, Yoon EJ, Lee SH, Lee MW, Lee DI, Choi YW, Joo SS, Won TJ, Kang HC.
  • Pharmaceutical composition for preventing and treating of metabolic bone disease comprising extract of Sophorae fructus. KR100509682B1 (August 23, 2005). Kwon SH, Hwang BS, Kim KH, Lee SH, Yoon EJ, Lee SH, Lee MW, Lee DI, Choi YW, Joo SS, Won TJ, Kang HC.