Findings may have broad translational potential A study led by Som Nanjappa at the University of Illinois College of Veterinary Medicine identifies a cellular target that may improve efficacy of vaccines designed to protect immunocompromised individuals from potentially deadly opportunistic infections. The study, recently published in the Journal of Immunology, demonstrates, using a mouse model,...
In Pathobiology, a diverse complement of disciplines takes an integrated systems approach encompassing all aspects of disease emergence, mechanisms of host-pathogen interactions, and novel approaches to disease prevention.
Expertise in the Department of Pathobiology spans epidemiology, microbiology, immunology, parasitology, virology, and comparative pathology.
Through its multidisciplinary approach, the department addresses complex problems in biomedical and veterinary sciences. Research emphasizes multi-host disease systems, with the goal of improving human and animal health at the individual and population levels in a broad social and environmental context.
In the veterinary professional degree program, the department teaches courses in both the basic science and clinical portions of the curriculum, fostering students’ ability to apply the fundamental tenets of disease mechanisms in the practice of clinical and diagnostic medicine.The Pathobiology graduate program produces leaders in biomedical research and education. The program accepts students from a variety of backgrounds, who have completed undergraduate or professional degrees, into programs leading to master’s and doctoral degrees. Graduate degrees are also offered in conjunction with the campus MD degree (Medical Scholars Program) and the college DVM degree (Veterinary Medical Scholars Program).
The department is home to a nationally recognized residency program in anatomic, clinical, or zoologic pathology, leading to board eligibility with the American College of Veterinary Pathology. The residency program can be combined with a PhD program. Virtually all graduate students receive tuition waivers and competitive stipends while participating in the teaching and research functions of the department.
Professional service, ranging from interpreting submissions to the college’s Veterinary Diagnostic Laboratory to developing continuing education courses in molecular biology and industrial toxicology and pathology, comprises a significant proportion of departmental activity.
Areas of Research
- Pathogenesis of enteric, respiratory, and reproductive diseases
- Molecular mechanisms of infection, host-pathogen interactions, and immunity
- Strategies for vaccine design and disease control
- Spatial and contextual aspects of health and illness, combining human, animal, and ecosystem health
- Mathematical modeling of infectious diseases to promote disease control
- Foreign animal disease prevention, preparedness, and response
- Virus biophysics
‘Like Toothpaste out of a Tube’ A new study reveals a previously unknown mechanism that governs whether viruses that infect bacteria will quickly kill their hosts or remain latent inside the cell. The discovery, reported in the journal eLife, also may apply to viruses that infect humans and other animals, the researcher said. “I found...
In one of the largest studies of its kind, researchers analyzed chikungunya and dengue outbreak data from 76 countries over a period of 50 years, focusing on regions across the Indian Ocean that are hard hit by these and other mosquito-borne infectious diseases. The analysis of 1959-2009 data revealed that population density and proximity to...