As a young veterinarian in Zambia, Dr. William Witola wanted to know why the baby cows he saw were dying from a parasite resisting all treatment. Decades later, the University of Illinois Veterinary Medicine researcher is designing small molecules to silence that same parasite’s gene expression, find potential drug targets and help end a disease...
Overview | Areas of Research | Faculty and Organization | News
Expertise in the Department of Pathobiology spans epidemiology, microbiology, immunology, parasitology, virology, and comparative pathology.
Through its multidisciplinary approach, the department addresses complex problems in biomedical and veterinary sciences. Research emphasizes multi-host disease systems, with the goal of improving human and animal health at the individual and population levels in a broad social and environmental context.
In the veterinary professional degree program, the department teaches courses in both the basic science and clinical portions of the curriculum, fostering students’ ability to apply the fundamental tenets of disease mechanisms in the practice of clinical and diagnostic medicine.The Pathobiology graduate program produces leaders in biomedical research and education. The program accepts students from a variety of backgrounds, who have completed undergraduate or professional degrees, into programs leading to master’s and doctoral degrees. Graduate degrees are also offered in conjunction with the campus MD degree (Medical Scholars Program) and the college DVM degree (Veterinary Medical Scholars Program).
The department is home to a nationally recognized residency program in anatomic, clinical, or zoologic pathology, leading to board eligibility with the American College of Veterinary Pathology. The residency program can be combined with a PhD program. Virtually all graduate students receive tuition waivers and competitive stipends while participating in the teaching and research functions of the department.
Professional service, ranging from interpreting submissions to the college’s Veterinary Diagnostic Laboratory to developing continuing education courses in molecular biology and industrial toxicology and pathology, comprises a significant proportion of departmental activity.
- Pathogenesis of enteric, respiratory, and reproductive diseases
- Molecular mechanisms of infection, host-pathogen interactions, and immunity
- Strategies for vaccine design and disease control
- Spatial and contextual aspects of health and illness, combining human, animal, and ecosystem health
- Mathematical modeling of infectious diseases to promote disease control
- Foreign animal disease prevention, preparedness, and response
Scientists may have unlocked the genetic code that determines why many patients with estrogen receptor-positive breast cancer fail to respond to the widely used drug tamoxifen. Patients who have higher levels of several nuclear transport genes – particularly the protein XPO1 – are more likely to be resistant to tamoxifen, resulting in the development of...
CHAMPAIGN, Ill. – As this year’s West Nile virus (WNV) transmission season begins, researchers from the University of Illinois have made available forecasting models they created for each of the nine climate areas of Illinois to predict mosquito infection rates on a weekly basis. Mosquitoes transmit WNV to humans. “When there is an increase in...