Comparative Biosciences

Comparative Biosciences is creating the future of science and medicine, extending new knowledge into real-life applications to improve the health of animals and people.

Welcome! Our department is a place where students and researchers pursue advances in comparative medicine, from basic science discovery through regulatory approval and successful application to human and animal health. We invite you to learn more about our work.

 Mission | Areas of Focus | Faculty | Key Collaborations | News

 

Mission

  • Instruct veterinary and graduate students in the pre-clinical sciences of gross anatomy, histology, developmental anatomy, neurobiology, physiology, pharmacology and toxicology
  • Conduct original, cutting-edge research on critical problems of animal, human, and environmental/ecosystem health
  • Sustain a university-leading program in comparative biomedical training and research
  • Offer clinical pharmacology and clinical toxicology diagnostic services and engage students in these activities
  • Participate in leadership and governance of professional and scientific societies as well as of the department, college, and university

 

Areas of Focus

The majority of our faculty work within several interconnected fields of interest. We bring a broad range of techniques and approaches to bear on these core areas: from micro-RNA to animal and human patient epidemiology to ecological assessments, and from cellular biology to applied clinical pharmacology and ecosystem health. Experimental models used in the department vary from stem cells to rodent and frog models to domestic animals, wildlife, and large prospective trials involving human patients.

Reproductive Biology

  • Current projects: Endocrine/reproductive biology and toxicology; uterine and placental biology; molecular mechanisms of early embryonic development; circadian rhythms in animal models of shift work and jet lag and impact on reproductive health; mechanisms regulating spermatogenesis and mouse models of male infertility
  • Faculty: Indrani Bagchi, Jodi Flaws, Rex Hess, CheMyong (Jay) Ko, Quanxi Li, Megan Mahoney, Wenyan Mei, Huanyu (Joe) Qiao, Prabhakara Reddi, Jing Yang

Developmental and Stem Cell Research

  • Current projects: Generation of 3D vascularized tissues for total replacement biologic products and other therapeutic purposes in regenerative medicine; the role of PTB (polypyrimidine tract binding protein) in regulating stem-cell-based tissue regeneration
  • Faculty: CheMyong (Jay) Ko, Wenyan Mei, Jing Yang

Neurobiology

  • Current projects: Impact of environmental and dietary compounds on neurodevelopment and on addictive potential of substances of abuse; effects of environmental factors and hormonal influences on cognitive functioning and neurotransmission
  • Faculty: Aditi Das, Paul Eubig, Makoto Inoue, Megan Mahoney, Susan Schantz
  • Center: Botanical Research Center

Ecosystem/Environmental Health

Comparative Pharmacology and Toxicology

  • Current projects: Stem cells for assessment of small molecule and nanoparticle pharmacology and toxicology; the interplay between  infectious agents and contaminants with wildlife populations; comparative drug disposition and pharmacokinetics; immunopharmacology and drug allergy; cancer chemotherapy
  • Faculty: Michael Biehl, Aditi Das, Michael Spinella

 

Faculty

Department Administration

Uwe Rudolph, Head
Email: urudolph@illinois.edu

Jodi Flaws, Assistant Head
Email: jflaws@illinois.edu

CheMyong “Jay” Ko, Director of Graduate Studies
Email: jayko@illinois.edu

Key Collaborations and Affiliations

 



 

News Comparative Biosciences News

[Zeeshan Fazal]

Postdoc Part of Study on Little Satellite with Big Benefits

Feb 15, 2019 / Comparative Biosciences News

Antibiotic Resistance in Space Dr. Zeeshan Fazal, a postdoctoral research associate currently working in the laboratory of Dr. Michael Spinella, comparative biosciences, received a commendation for work he participated in while at Stanford University. The Group Achievement Award was presented to the E. coli AntiMicrobial Satellite (EcAMSat) mission team. Their project, which took place on...

[Dr. Jodi Flaws and graduate student Katie Chiang]

Phthalate May Impair Fertility in Female Mice

Feb 7, 2019 / Comparative Biosciences News

Many Rodent Studies Link Phthalates to Health Problems A phthalate found in many plastic and personal care products may decrease fertility in female mice, a new study found. Researchers at the University of Illinois found that giving female mice oral doses of the phthalate DiNP for 10 days disrupted their reproductive cycles, decreasing their ability...

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