Janice Bahr

Janssen, S, Dalponte, M., Lee, K.H., Boltz, D., Nakai, M., Bunick D., and Bahr, J.M. (2006) Ion transporters for fluid reabsorption in the rooster epididymal region: Detection of mRNAs and proteins of Na+, K+-ATPase, carbonic anhydrase II and sodium hydrogen exchanger-3. Animal Reprod Sci 95:331-337.

Bahr, J.M., Nakai, M., Rivera, A., Walsh, J., Evans, G.L., Lotinun, S., Turner, R.T., Black, M., Jeffery, E.H. (2004) Dietary soy protein and isoflavones: Minimal beneficial effects on bone and no effect on the reproductive tract of sexually mature ovariectomized Sprague-Dawley rats. Menopause 12:165-173.

Paul S. Cooke

Cooke P.S., Holsberger D., Cimafranca M.A., Meling D., Beals C., Nakayama K., Nakayama K., Kiyokawa H. (2007) The F box protein Skp2 regulates adipose mass and adipocyte number in vivo. Obesity 15:1400-1408.

Cooke P.S., Gore A.C., Crews D., Simon L, Cimafranca M.A., (2008) Environmental Endocrine Disruptors and Male Reproductive Toxicology. In: Comprehensive Toxicology, 2nd edition, Volume 11, P. Hoyer and J. Richburg (eds.), Elsevier Press, Oxford, England (in press).

Jodi Flaws

Hernández-Ochoa, I., Karman, B.N. and Flaws, J.A.  The role of the aryl hydrocarbon receptor in the female reproductive system. Special issue: Biological functions of the aryl hydrocarbon receptor.  Biochem Pharmacol 2008 in press.

William Helferich

Ju, Y.H., Doerge, and Helferich, W.G. (2008). A dietary supplement for female sexual dysfunction, Avlimil, stimulates the growth of estrogen-dependent breast tumors (MCF-7) implanted in ovariectomized athymic nude mice. Food Chem. Toxicology. 46, 1, 310-320.

Wang V.C., Sable H.J., Ju Y.H., Allred C.D., Helferich W.G., Korol D.L., Schantz S.L. (2008). Effects of chronic estradiol treatment on delayed spatial alternation and differential reinforcement of low rates of responding. Behav Neurosci. 2008 Aug;122(4):794-804.

Ju, Y.H., Doerge, D.R., Hartman, J.A., Kwak, J., and Helferich, W.G.. (2008) Dietary genistein negates the inhibitory effect of letrozole on the growth of aromatase-expressing estrogen-dependent human breast cancer cells (MCF-7Ca) implanted in ovariectomized athymic mice. Carcinogenesis. Advance Access published on July 16, 2008; doi: doi:10.1093/carcin/bgn161.

Wu R, Zhang L, Hoagland M.S., and Swanson H. (2007) “Lack of the AhR leads to impaired activation of AKT/PKB and enhanced sensitivity to apoptosis induced via the intrinsic pathway.” J Pharmacol Exp Ther. In Press.

Ju, Y.H., Allred, K.F., Allred, C.D., and Helferich, W.G., (2006) Genistein Stimulates Growth of Human Breast Cancer Cells in a Novel, Postmenopausal Animal Model, with Low Plasma Estradiol Concentrations. Carcinogenesis Jun 27(6):1292-9.

Putt K.S., Chen G.W., Pearson J.M., Sandhorst J.S., Hoagland M.S., Kwon J.T., Hwang S.K., Jin H, Churchwell M.I., Cho M.H., Doerge D.R., Helferich W.G., Hergenrother P.J. (2006) Small-molecule activation of procaspase-3 to caspase-3 as a personalized anticancer strategy. Nat Chem Biol. 2(10):543-50.

Ju, Y.H., Fultz, M.J., Allred, K.F., Doerge, D.R., and Helferich, W.G., (2006) Effects of dietary daidzein and its metabolite, equol, at physiological concentrations on the growth of estrogen-dependent human breast cancer (MCF-7) tumor implanted in ovariectomized athymic mice. Carcinogenesis  27(4):856-63.

Allred, C.D., Twaddle, N.C., Allred, K.F., Churchwell, M.I., Ju, Y.H., Helferich, W.G., and Doerge, D. R. (2005) Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized Balb/c mice. J. Agric. Food Chem. 53(22):8542-8550.

Allred, C.D., Twaddle, N.C., Allred, K.F., Churchwell, M.I., Ju, Y.H., Helferich, W.G., and Doerge, D.R. (2004) Soy processing affects metabolism and disposition of dietary isoflavones in ovariectomized Balb/c mice. Journal of Nutrition.

Selvaraj, V., Zakroczymski, M.A., Naaz, A, Mukai, M, Ju, Y.H., Doerge, D.R., Katzenellenbogen, J.A., Helferich, W.G., and Cooke, P.S. (2004) Estrogenicity of the isoflavone metabolite equol on reproductive and non-reproductive organs in mice. Biology of Reproduction 71:966-972.

Allred, C.A., Allred, K.F., Ju, Y.H., Doerge, D.R., and Helferich, W.G. (2004) Soy processing influences growth of estrogen-dependent breast cancer tumors. Carcinogenesis 25:1649-1657.

Ju, Y.H., Clausen, L.M., Almada, A.L., and Helferich, W.G., (2004) beta-Sitosterol, beta-sitosterol glucoside, and a mixture of beta-sitosterol and beta-sitosterol glucoside modulate the growth of estrogen-responsive breast cancer cells in vitro and in ovariectomized athymic mice. Journal of Nutrition 134(5):1145-1151.

Muthyala, R.S., Ju, Y.H., Sheng, S., Williams, L.D., Doerge, D.R., Helferich, W.G., and Katzenellenbogen, J.A. (2004) Equol, a natural estrogenic metabolite from soy isoflavones: Convenient synthesis and resolution of R- and S-equol and their biological activity through the estrogen receptors alpha and beta. Bioorganic and Medicinal Chemistry 12(6):1559-1567.

Allred, C.A., Allred, K. F., Ju, Y.H., Doerge, D.R., Schantz, S., Korol, D., and Helferich, W.G. (2004) Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis 25(2):211-218.

Ju, Y.H., Doerge, D.R., Allred, K.F., Allred, C.D., and Helferich, W.G. (2002) Dietary genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice. Cancer Research 62:2474-2477.