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Welcome    欢迎    Bienvenido    مرحبا بك   환영합니다    ברוך הבא    Bienvenue   Herzlich willkommen

Dr. CheMyong Jay KoThank you for visiting our laboratory, a place for junior scientists who have passion for science. This is their laboratory for learning scientific skills, experimenting new ideas, growing to excellency and developing new knowledge for all. These goals are achieved by working on a few projects. One of the main themes of the laboratory is to elucidate the mechanism governing the breakdown and rupture of the follicle during the ovulatory process. This process is activated by a surge of luteinizing hormone (LH), a pituitary gonadotropin, which triggers dramatic changes in the ovary at molecular, biochemical, and physical levels, eventually leading to the rupture of a mature follicle, releasing an egg. However, many of the key factors involved in and the mechanism governing the process of LH release and follicle rupture are yet to be unveiled. Our research team aims to reveal the LH-induced intraovarian molecular events and the roles that ovarian steroid hormones play in this process, ultimately to help women who suffer from infertility caused by ovulatory defects. Other exciting projects include reproductive toxicology, novel roles that sex steroids play in reproductive/non-reproductive tissues and generation of novel transgenic animals and databases for shared uses. Please take a moment to explore our projects, meet our people and see some funny or serious photos taken by our team members. Please contact any of our team members if you are interested in our projects or want to collaborate with us. You can find their email contacts and projects in the ‘People’  section.

News From the Lab:

2018 Endocrine Society Meeting in Chicago, IL

The Ko laboratory will be attending the Endocrine Society Meeting from March 17 to 19. Chris Park will be giving an oral presentation titled “Progesterone Receptor, a Dual Player for Triggering Ovulation and Protecting the Ovary from Ovulatory Inflammation” on March 17, 2018 starting as 12:15 PM. Radwa Barakat was invited to […]

Welcome to the family, Tauseef Shah!

Tauseef Shah, a PhD candidate in Molecular and Integrative Physiology, joined our laboratory just before winter break. He is from Srinagar Kashmir, a place located at the northernmost end of India, surrounded by China, Pakistan, and Afghanistan. He lived most of his life in Kashmir and received his degree in veterinary medicine in 2011. After […]

Generation and characterization of an estrogen receptor alpha-iCre knock-in mouse

Chris Park’s manuscript titled “Generation and characterization of an estrogen receptor alpha-iCre knock-in mouse” was recently published and is now available in Genesis. ESR1-iCre mice will also be available at the Jackson Laboratory soon, so keep on the lookout for updates.