Earlier this year, the Champaign-Urbana Public Health District identified Tularemia, also known as Rabbit Fever, in several dead squirrels from the Champaign area. While Tularemia can affect people and animals, the lagomorph (rabbits and hares) and rodent populations are most susceptible to the disease. Both Eastern Cottontails (Sylvilagus floridanus) and Swamp Rabbits (Sylvilagus aquaticus) are native to the state of Illinois and could possibly act as sources of the disease.
What Is Rabbit Fever and How Does it Spread?
Rabbit Fever or Tularemia is a disease caused by Francisella tularensis, a gram-negative bacterium that is found in mud, dead animals, and water. Francisella tularensis can survive in the environment for about 4 months or up to three years in frozen meats, however, it is easily killed by disinfectants. There are two types of Francisella tularensis, Francisella tularensis biovar tularensis (Type A) and Francisella tularensis biovar holarctica (Type B). Type A is more harmful than Type B and is found in the North American region while Type B is less harmful and found in Europe and Asia regions.
Rabbit fever can be spread by direct contact with rabbits or other infected mammals via bite wounds, handling contaminated skin or paws, or in laboratory exposure. It can also spread via tick bites and inhalation of contaminated dust or soil. Additionally, it can spread through contaminated water and eating undercooked meat from an infected animal.
Signs and Symptoms in People and Pets
Tularemia can cause many different signs and symptoms depending on how the bacteria entered the body. The most common symptom in people is Ulceroglandular, which is caused by tick bites or after handling a contaminated animal. Ulceroglandular symptoms can be described as a formation of skin ulcers and swelling of lymph nodes in the arm pit or groin areas. Symptoms are also accompanied by a fever as high as 104°F.
Tularemia signs and symptoms in cats include fever, depression, appetite loss, and oral ulcers. Symptoms and signs in dogs include fever, loss of appetite, nasal and eye discharge, and abscess formation at the site of infection. Horses also exhibit signs of fever and depression, additionally they can show signs of trouble breathing, stiffness and swelling of the limb.
How to Prevent the Spread of Rabbit Fever
The spread of Rabbit Fever can be prevented in a multitude of ways, including the use of insect repellents, promptly removing ticks, wearing long pants and sleeves while outdoors, wearing PPE such as gloves and mask when mowing and working in your yard, and by avoiding drinking untreated surface water. Additionally, the spread of Rabbit Fever in pets can be prevented by limiting their exposure to wildlife, especially rabbits and rodents, and making sure that they are on Flea/Tick prevention year-round.

Sources
Tularemia, U.S Centers for Disease and Control (2024, May 15th). Retrieved October 17, 2025, from https://www.cdc.gov/tularemia/about/index.html
Deaths Reported in Several Area Squirrels, Tularemia Identified, Champaign-Urbana Public Health District (2025, April 16th), Retrieved October 17, 2025, from https://www.c-uphd.org/press-release/2025/deaths-reported-in-several-area-squirrels-tularemia-identified.html
Tularemia, Cleveland Clinic (2022, August 25th) Retrieved October 17, 2025, from https://my.clevelandclinic.org/health/diseases/17775-tularemia
Tularemia in animals, AVMA, Retrieved October 17, 2025, from https://www.avma.org/resources-tools/animal-health-and-welfare/animal-health/tularemia-animals#:~:text=Enlarged%20liver,How%20is%20tularemia%20transmitted?
Written By: Irene J., Class of 2028






