NEWS FROM THE JAROSINSKI LAB
Dr. Yung-Tien (Yvette) Tien published her first first author paper on Temperature-induced Reactivation of Marek’s disease virus-transformed T cells ex vivo. Dr. Haji Akbar is also a co-author.
Dr. Nagendraprabhu Ponnuraj published his work in collaboration with members from the USDA and VCM on the regulation of US10 by CHPK in PLOS PATHOGENS. Dr. Haji Akbar is also a co-author.
Dr. Haji Akbar published his work on a USDA Hatch project focused on Purinergic Signaling during Marek’s disease in chickens. Julia Fasick and Dr. Ponnuraj are also co-authors for their work on the project.
Dr. Jarosinski was recently interviewed for his laboratory’s paper published in Virulence last month where they showed that MD vaccines and MDV can infect the same cells in vivo that can result in functional complementation. See the interview here.
Dr. Jarosinski was also interviewed at WATT Poultry.com about this work. It can be found here.
Congratulations to Huai Xu and Andrea Krieter on their joint paper on how vaccines and virulent viruses can infect the same cells in vivo that can result in functional complementation. Drs. Ponnuraj and Tien are also authors along with Dr. Taejoong Kim from the USDA. This paper was published in Virulence.
Congratulations to Andrea Krieter on her second 1st author paper on CHPK, this time studying its importance in GaHV3 transmission. Huia Xu and Dr. Haji Akbar are also authors. This paper was published in Viruses for their special issue “Replication and Spread of Alphaherpesvirus.”
Congratulations to Widaliz Vega Rodriguez on successfully defending her thesis entitled “The role and regulation of glycoprotein C during herpesvirus pathogenesis”
Drs. Jarosinski and McAllister obtained an Animal Health and Disease grant from the USDA to temporal expression of viral genes. Dr. Milton McAllister is an Associate Professor at the University of Adelaide in Australia doing research in Dr. Jarosinski’s lab for his sabbatical leave. The grant will begin in December 2021 and end in September 2023.
Drs. Jarosinski and Tien obtained a Hatch grant from the USDA to study reactivation of Marek’s disease virus. This money will provide money to examine the viral and cellular gene expression during reactivation of MDV in transformed T cells. The grant will begin in December 2021 and end in September 2023.
Congratulations to Widaliz Vega Rodriguez on publishing her third paper on glycoprotein C working toward the completion of her PhD. This paper was published in Viruses for their special issue “Replication and Spread of Alphaherpesvirus.”
Congratulations to Widaliz Vega Rodriguez and Huai Xu on their co-first authorship on the most recent paper published from our lab in Scientific Reports.
Congratulations to Widaliz Vega Rodriguez on winning the Paul B. Doby Award given to a College of Veterinary Medicine graduate student for excellence in infectious disease research. The award consists of a certificate and $2,000 (-taxes).
Widaliz won one of four American College of Veterinary Microbiologists (ACVM) Awards given to graduate students presenting at CRWAD this year. Congratulations!
Andrea Krieter and Widaliz Vega Rodriguez presented during the 2020 CRWAD held virtually from December 5-8th, 2020. Andrea presented “Marek’s disease alphaherpesvirus UL13, virion protein US10, and cellular LY6E in horizontal transmission,” while Widaliz presented “The role of the conserved alphaherpesvirus glycoprotein C in host-to-host transmission.”
All students presented their research at the 2020 PATH Graduate Student Expo on August 21st. Widaliz Vega Rodriguez presented her research “The role of avian alphaherpesvirus conserved glycoprotein C (gC) proteins in turkey alphaherpesvirus (HVT) horizontal transmission.” Dr. Yvette (Yung-Tien) Tien presented her research, “Understanding the transition from early to late viral gene expression during herpesvirus reactivation.” Andrea Krieter presented her research, “Determining the role Marek’s disease virus (MDV) conserved herpesvirus protein kinase (CHPK) plays in host-to-host transmission.” Huia Xu presented “The role of Marek’s disease vaccines’ glycoprotein C in replication and transmission.”
Yvette’s presentation was voted honorable mention. Congratulations!
Dr. Jarosinski is co-author on a paper recently published in a Special Issue of Pathogens. Lead author was Dr. Caitlin Burrell who completed her Master’s in the Zoological Pathology Program in the UIUC College of Veterinary Medicine this year.
Dr. Jarosinski is co-author on a paper recently accepted for publication in the Journal of Virology.
Congratulations to Widaliz Vega-Rodriguez for receiving a Graduate Teaching Assistantship as a Group Leader for the Summer Predoctoral Institute (SPI) in the Graduate College this summer.
The Summer Predoctoral Institute (SPI) at the University of Illinois at Urbana-Champaign (Illinois) provides incoming graduate students from U.S. populations underrepresented at Illinois with an early introduction to graduate study and an opportunity to work with a summer research advisor in their department. SPI will assist participants in becoming socialized into the departmental culture, as well as afford them an opportunity to prepare for the rigors of their graduate program.
During the six-week summer session, each participant will enroll in an independent study course directed by their advisor and fulfill virtual participation with training and acclimation activities. Students will participate in a series of online seminars on research writing and grad school culture, which will respectively provide a foundation for dissertation research and enable the student to become acquainted with the expectations of their graduate program.
Congratulations to Dr. Yung-Tien (Yvette) Tien on winning the People’s Choice Award for the 2020 Image of Research competition!
Marek’s disease is a viral epidemic disease that causes billions of dollars in economic loss in the poultry industry. It is caused by Gallid alphaherpesvirus 2 which transforms T lymphocytes into lymphomas. The infection of feather follicular epithelial cells starts the spreading of virus from chicken to chicken by shedding viral particles so when chickens flap their wings, the virus goes into the air and other chickens inhale the virus and become infected. Everything happens naturally and unseen, which is the beauty of microbiology.
Congratulations to Zeidy Garcia on being awarded a James Scholar Preble Research Award by the Honors Council of the College of Liberal Arts and Sciences for Spring 2020 semester!
Congratulations to Dr. Yvette Tien for her entry for University of Illinois Graduate College’s 2020 Image of Research Award making it to the top 25 images.
The image can be viewed here. https://blogs.illinois.edu/view/8606/807665
Voting for the People’s Choice Award is here and closes April 30th at 5 PM.
Congratulations to Andrea Krieter on winning the Paul B. Doby Award given to a College of Veterinary Medicine graduate student for excellence in infectious disease research. She will be presented the award as soon as we are able to gather as a group again.
Congratulations to Andrea Krieter on getting her first first author paper accepted in the Journal of Virology.
Dr. Jarosinski was invited to give a seminar at Poultry Diagnostic and Research Center in the Department of Population Health at the University of Georgia – Athens.
All students presented their research at the 2019 PATH Graduate Student Expo on August 23rd. Widaliz Vega Rodriguez presented her research “Role of avian alphaherpesvirus conserved glycoprotein C (gC) in Marek’s disease virus (MDV) horizontal transmission.” Dr. Yvette (Yung-Tien) Tien presented her research, “Characterization of Marek’s disease virion in vitro and in vivo.” Andrea Krieter presented her research, “Determining the role of phosphorylation in Marek’s disease virus (MDV) conserved herpesvirus protein kinase (CHPK).
Widaliz won first prize for best presentation, while Andrea won 3rd place and Yvette was honorable mention. Congratulations to all on jobs well done!
Congratulations to Widaliz Vega Rodriguez on publishing her first first author paper.
Dr. Jarosinski traveled to Washington, D.C. to represent the UIUC College of Veterinary Medicine, along with two representatives from ACES, at the 2019 Agriculture Research Congressional Exhibition and Reception to demonstrate the value USDA-NIFA funding has provided the agricultural world.
Dr. Yvette (Yung-Tien) Tien, Widaliz Vega Rodriguez, and Andrea Krieter presented their research at the 2019 College of Veterinary Medicine Research Day. Andrea presented both a poster and talk, while Widaliz presented two posters and Yvette presented one poster.
Congratulations to Andrea that won 3rd place for the best presentation!
Both Katherine Fleck (Senior) and Zeidy Garcia (Junior) presented their research at the Illinois Undergraduate Research Symposium on April 18th .
Dr. Ponnuraj’s paper on the role of UL54 (ICP27) during in vitro and in vivo replication was recently published in the Journal of Virology.
Dr. Jarosinski presented a seminar at the UIUC School of Molecular and Cellular Biology Microbiology Seminar Series on the role conserved herpesvirus genes play in host-to-host transmission.
Dr. Jarosinski’s NIH/USDA grant proposal to the PAR-16-366 Dual Purpose with Dual Benefit will be funded by the USDA beginning in April of 2019 until 2024. This grant is in collaboration with Dr. Charles Grose at the University of Iowa and will focus on the role the alphaherpesvirus conserved glycoprotein C (gC) plays in host specificity of avian and human herpesviruses.
Above shows the model systems being used to study replication and transmission of herpesviruses. A shows feathers infected with Marek’s disease virus (MDV) expressing fluorescent protein in feather follicle epithelial (FFE) cells. B shows varicella-zoster virus (VZV) infected human foreskins in culture expressing fluorescent protein.
Michael Brooks presented his poster for the Summer Research Training Program on July 31st, 2018 and traveled to Texas A&M University August 2-4, 2018 to present his poster at the National Veterinary Scholars Symposium. His work with Yung-Tien (Yvette) Tien focused on development of Marek’s disease virus (MDV) transformed cell lines and their characterization using flow cytometry and immunofluorescence assays. Michael will continue to work on this project in his limited free time during his second year of vet school.
Dr. Jarosinski attended the 43rd Annual International Herpesvirus Workshop (http://www.herpesvirusworkshop.com/2018/) in Vancouver, BC, Canada July 21st-July 25th. He presented 3 posters and gave 1 seminar during the Veterinary Satellite Workshop.
A collaborative paper between Drs. Jarosinski and Grose on cellular stress responses to VZV in human skin was recently published in Open Forum Infectious Disease.
Widaliz won the Outstanding Scholar Award for the Summer Pre-doctoral Institute (SPI) during the summer of 2017 for her work on determining the chicken-to-turkey host specificity of herpesviruses.
Dr. Jarosinski’s chapter in Cell Biology of Herpes Viruses on Interindividual Spread of Herpesviruses is now available.
Dr. Jarosinski was invited to speak at the 17th Annual Rocky Mountain Virology Meeting held on the CSU Mountain Campus in Pingree Park Sept. 22-24th, 2017. His talk was titled, “Understanding host-specificity during herpesvirus host-to-host transmission.”
Dr. Yvette (Yung-Tien) Tien received a fellowship from the Taiwanese Ministry of Education to pursue Pathology and her PhD in Dr. Jarosinski’s laboratory starting in the fall of 2017.