Cell Reports March 8th 2022

Figure contributed by Coni Hoerndli

Noncanonical genomic imprinting in the monoamine system determines naturalistic foraging and brain-adrenal axis functions

See press release.

“The revelation that maternal and paternal alleles of the same gene along the brain-adrenal axis could have disparate, or possibly even antagonistic, phenotypic consequences on behavior is an intriguing observation,” says the paper’s first author, Paul Bonthuis, […]

Dopa decarboxylase is a genetic hub of parental control over offspring behavior

Dopa decarboxylase (Ddc) is a genetic hub of parental control over offspring behavior

Hop on over to bioRxiv to see Dr. Bonthuis’ 2020 paper on how Ddc, a monoaminergic regulator, is influenced by parentage and in turn effects social behavior. He found maternal and paternal Ddc alleles control distinct behavioral sequences. Additionally, Ddc exhibits dominant expression of the maternal […]