PUBLICATIONS
Selected manuscripts
Santacruz-Márquez, R., Sánchez Peña, L., Flaws, J.A, Hernández-Ochoa, I. (2025) The effect of TiO2 nanoparticles on antral follicles is dependent on the nanoparticle internalization rate. Toxicological Sciences Dec 11:kfae155. doi: 10.1093/toxsci/kfae155.
Gokyer, D., Laws, M.J., Kleinhans, A., Riley, J.K., Flaws, J.A., Babayev, E. (2025) Phthalates are detected in the follicular fluid of adolescents and oocyte donors with associated changes in the cumulus cell transcriptome, Fertility and Sterility Science 6:30-41.
Santacruz-Márquez, R., Safar, A., Laws, M.J., Fletcher, E.J., Meling, D.D., Nowak, R.A., Raetzman, L.,T., Flaws, J.A. (2025) Dietary exposure to di(2-ethylhexyl) phthalate (DEHP) for 6 months alters makers of female reproductive aging in mice. Biology of Reproduction 112:191-202.
Oladosu, J. and Flaws, J.A. (2025) The impact of neonicotinoid pesticides on reproductive health. Toxicological Sciences 203(2):131-146. doi: 10.1093/toxsci/kfae138.
Fletcher, E.J., Stubblefield, W.S., Seaton, T.A., Safar, A.M., Dean, A.E., Laws, M.J., Brehm, E., Flaws, J.A. (2025) Prenatal exposure to an environmentally relevant phthalate mixture alters oxidative stress, apoptosis, cell cycle regulators, and steroidogenic factors in the ovaries of F1 mice. Reproductive Toxicology 132:108858.
Silva, A.V., Tarvainen, I., Öberg, M., Laws, M., Hannon, P., Flaws, J.A., Damdimopoulou P. (2025) Bayesian benchmark dose modeling analysis and derivation of points of departure for female reproductive toxicity following exposure to di(2-ethylhexyl) phthalate effects on reproductive hormones, folliculogenesis, and estrous cyclicity. Toxicological Sciences 206”30-45.
Parra Forero, Y..L., Hernández Ochoa, I., Flaws, J.A., Nowak, R.A. (2025) Oral exposure to di(2-ethylhexyl) phthalate (DEHP) alters the expression of GATA6, OCT4, and CDX2 in blastocysts and decreases the rate of implantation in a murine model. Toxicological Sciences 206:68-85.
Shukla, R., Kannan, A., Laws, M.J., Flaws, J.A. Bagchi, M.K., Bagchi, I.C. (2025) Exposure to phthalates enhances estrogen and beta-catenin signaling pathways, leading to endometrial hyperplasia in mice. Toxicological Sciences 206:58-67.
Beal, J.R., Bhurke, A., Katzenellenbogen, J., Yu, J., Flaws, J., Bagchi, I.C., Bagchi, M.K. (2025) Phthalates impair estrogenic regulations of HIF2 and extracellular vesicle secretion by human endometrial stromal cells. Endocrinology pr 22;166(6):bqaf087. doi: 10.1210/endocr/bqaf087.
Laws, M.J., Kramer, S., Gonyea, T., Huff, J., Edwards, L., Tarvainen, I., Damdimopoulou, P., Flaws. J.A. (2025) Epidemiologically relevant phthalate mixture and mono(2-ethyl-5-hydroxyhexyl) phthalate exposure alter cell energy metabolism in primary murine granulosa cells. Reproductive Toxicology Aug;135:108938. doi: 10.1016/j.reprotox.2025.108938.
Fletcher, E.J., Stubblefield, W.S., Seaton, T.A., Santacruz-Márquez, R., Laws, M.J., Gonyea, T.M., Dean, A.E., Li, Z., Flaws, J.A. (2025) Neonatal exposure to an environmentally relevant phthalate mixture alters ovarian function in mice. Toxicology and Applied Pharmacology Jul;500:117372. doi: 10.1016/j.taap.2025.117372.
Nikanfar, S., Leonel, E.C., Damdimopoulou, P., Flaws, J.A., Amorim, C.A. (2025) Effects of phthalate exposure on ovarian extracellular matrix composition: insights from a 3D spheroid model. Environmental Research Aug 15;279(Pt 1):121797. doi: 10.1016/j.envres.2025.121797.
Magosso, N., Vieira de Souza, P., Aquino, A.M., Rocha, V.A., Fioretto, M.N., Costa, L.G.A., de Campos, S.G.P., Barbisan, L.F., Justulin, L.A., Flaws, J.A., Scarano, W.R. (2025) Maternal exposure to an environmental relevant phthalate mixture modulates the steroidogenic genes in the adrenal glands throughout postnatal development of male rats. Environmental Toxicology 40:1294-1307.
Souza, P.V., Aquino, A.M., Alonso-Costa, L.G., Magosso, N., Oliveira, M.A.F., Rocha, V.A., Fioretto, M.N., Moreira, M.F., Pinha, V.C., Caxali, G.H., Justulin, L.A., Flaws, J.A., Scarano, W. (2025) Maternal phthalate exposure alters the prostate proteome in offspring rats: linking omics insights to prostate cancer risk in humans. Archives of Medical Research: Special Issue on DOHaD and Environmental Contaminants Sep 6;57(2):103297. doi: 10.1016/j.arcmed.2025.103297.
Dean, A.E., Flaws, J.A. (2025) The role of the aryl hydrocarbon receptor in ovarian development, function, and disease. Biology of Reproduction Aug 30:ioaf201. doi: 10.1093/biolre/ioaf201.
Mourikes, V.E., Lee, C., Oladosu, J.I., Deviney, A., Stubblefield, W., Laws, M.J., Mahoney, M., Flaws, J.A. (2025) The effects of imidacloprid exposure on the mouse ovary in vivo. Reproductive Toxicology Oct;137:109045. doi: 10.1016/j.reprotox.2025.109045.
Lee, C., Quinto, J., Poteat, T., Mourikes, V., Flaws, J.A., Mahoney, M.M. (2025) Prenatal exposure to imidacloprid affects cognition and anxiety-related behaviors in male and female CD-1 mice. Toxics Oct:137:109045. doi: 10.1016/j.reprotox.2025.109045.