{"id":1062,"date":"2016-12-05T20:54:50","date_gmt":"2016-12-05T20:54:50","guid":{"rendered":"http:\/\/vivid7.vetmed.illinois.edu\/wp\/inoue-lab\/?page_id=2"},"modified":"2021-06-30T18:51:28","modified_gmt":"2021-06-30T18:51:28","slug":"publications","status":"publish","type":"page","link":"https:\/\/vetmed.illinois.edu\/spinella-freemantle-lab\/publications\/","title":{"rendered":"Freemantle Publications"},"content":{"rendered":"

FREEMANTLE PUBLICATIONS<\/h2>\n<\/div>
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  1. Between a Rock and a Hard Place: An Epigenetic-Centric View of Testicular Germ Cell Tumors.<\/a>\n
    Singh R, Fazal Z,\u00a0Freemantle SJ<\/b>, Spinella MJ.<\/span>Cancers (Basel). 2021 Mar 25;13(7):1506. doi: 10.3390\/cancers13071506.<\/span><\/div>\n<\/li>\n
  2. The Ubiquitin-Specific Peptidase USP18 Promotes Lipolysis, Fatty Acid Oxidation, and Lung Cancer Growth.<\/a>\n
    Liu X, Lu Y, Chen Z, Liu X, Hu W, Zheng L, Chen Y, Kurie JM, Shi M, Mustachio LM, Adresson T, Fox S, Roszik J, Kawakami M,\u00a0Freemantle SJ<\/b>, Dmitrovsky E.<\/span>Mol Cancer Res. 2021 Apr;19(4):667-677. doi: 10.1158\/1541-7786.MCR-20-0579. Epub 2020 Dec 30.<\/span><\/div>\n<\/li>\n
  3. A Novel CDK2\/9 Inhibitor CYC065 Causes Anaphase Catastrophe and Represses Proliferation, Tumorigenesis, and Metastasis in Aneuploid Cancers.<\/a>\n
    Kawakami M, Mustachio LM, Chen Y, Chen Z, Liu X, Wei CH, Roszik J, Kittai AS, Danilov AV, Zhang X, Fang B, Wang J, Heymach JV, Tyutyunyk-Massey L,\u00a0Freemantle SJ<\/b>, Kurie JM, Liu X, Dmitrovsky E.<\/span>Mol Cancer Ther. 2021 Mar;20(3):477-489. doi: 10.1158\/1535-7163.MCT-19-0987. Epub 2020 Dec 4.<\/span><\/div>\n<\/li>\n
  4. Hypermethylation and global remodelling of DNA methylation is associated with acquired cisplatin resistance in testicular germ cell tumours.<\/a>\n
    Fazal Z, Singh R, Fang F, Bikorimana E, Baldwin H, Corbet A, Tomlin M, Yerby C, Adra N, Albany C, Lee S,\u00a0Freemantle SJ<\/b>, Nephew KP, Christensen BC, Spinella MJ.<\/span>Epigenetics. 2020 Oct 30:1-14. doi: 10.1080\/15592294.2020.1834926. Online ahead of prin<\/span><\/div>\n<\/li>\n
  5. TRIGGERING ANAPHASE CATASTROPHE TO COMBAT ANEUPLOID CANCERS.<\/a>\n
    Dmitrovsky E, Kawakami M, Liu XI,\u00a0Freemantle SJ<\/b>, Kurie JM.<\/span>Trans Am Clin Climatol Assoc. 2020;131:82-94.<\/span><\/div>\n<\/li>\n
  6. Mechanisms of cisplatin sensitivity and resistance in testicular germ cell tumors.<\/a>
    \nSingh R, Fazal Z, Freemantle SJ,\u00a0Spinella MJ.<\/strong>
    \nCancer Drug Resist<\/span>. 2019;2(3):580-594. doi: 10.20517\/cdr.2019.19. Epub 2019 Sep 19.
    \nPMID: 31538140
    \n    Similar articles<\/a><\/li>\n
  7. Epigenetic Remodeling through Downregulation of Polycomb Repressive Complex 2 Mediates Chemotherapy Resistance in Testicular Germ Cell Tumors.<\/a>
    \nSingh R, Fazal Z, Corbet AK, Bikorimana E, Rodriguez JC, Khan EM, Shahid K, Freemantle SJ, Spinella MJ.
    \nCancers (Basel)<\/span>. 2019 Jun 8;11(6). pii: E796. doi: 10.3390\/cancers11060796.
    \nPMID: 31181810 [PubMed] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  8. Evidence for the ISG15-Specific Deubiquitinase USP18 as an Antineoplastic Target.<\/a>
    \nMustachio LM, Lu Y, Kawakami M, Roszik J, Freemantle SJ, Liu X, Dmitrovsky E.
    \nCancer Res<\/span>. 2018 Feb 1;78(3):587-592. doi: 10.1158\/0008-5472.CAN-17-1752. Epub 2018 Jan 17. Review.
    \nPMID: 29343520 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  9. G0S2 represses PI3K\/mTOR signaling and increases sensitivity to PI3K\/mTOR pathway inhibitors in breast cancer.<\/a>
    \nYim CY, Bikorimana E, Khan E, Warzecha JM, Shin L, Rodriguez J, Dmitrovsky E, Freemantle SJ, Spinella MJ.
    \nCell Cycle<\/span>. 2017;16(21):2146-2155. doi: 10.1080\/15384101.2017.1371884. Epub 2017 Sep 14.
    \nPMID: 28910567 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  10. Deubiquitinase USP18 Loss Mislocalizes and Destabilizes KRAS in Lung Cancer.<\/a>
    \nMustachio LM, Lu Y, Tafe LJ, Memoli V, Rodriguez-Canales J, Mino B, Villalobos PA, Wistuba I, Katayama H, Hanash SM, Roszik J, Kawakami M, Cho KJ, Hancock JF, Chinyengetere F, Hu S, Liu X, Freemantle SJ, Dmitrovsky E.
    \nMol Cancer Res<\/span>. 2017 Jul;15(7):905-914. doi: 10.1158\/1541-7786.MCR-16-0369. Epub 2017 Feb 27.
    \nPMID: 28242811 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  11. The ISG15-specific protease USP18 regulates stability of PTEN.<\/a>
    \nMustachio LM, Kawakami M, Lu Y, Rodriguez-Canales J, Mino B, Behrens C, Wistuba I, Bota-Rabassedas N, Yu J, Lee JJ, Roszik J, Zheng L, Liu X, Freemantle SJ, Dmitrovsky E.
    \nOncotarget<\/span>. 2017 Jan 3;8(1):3-14. doi: 10.18632\/oncotarget.13914.
    \nPMID: 27980214 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  12. Refractory testicular germ cell tumors are highly sensitive to the second generation DNA methylation inhibitor guadecitabine.<\/a>
    \nAlbany C, Hever-Jardine MP, von Herrmann KM, Yim CY, Tam J, Warzecha JM, Shin L, Bock SE, Curran BS, Chaudhry AS, Kim F, Sandusky GE, Taverna P, Freemantle SJ, Christensen BC, Einhorn LH, Spinella MJ.
    \nOncotarget<\/span>. 2017 Jan 10;8(2):2949-2959. doi: 10.18632\/oncotarget.13811.
    \nPMID: 27936464 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  13. Dinaciclib Induces Anaphase Catastrophe in Lung Cancer Cells via Inhibition of Cyclin-Dependent Kinases 1 and 2.<\/a>
    \nDanilov AV, Hu S, Orr B, Godek K, Mustachio LM, Sekula D, Liu X, Kawakami M, Johnson FM, Compton DA, Freemantle SJ, Dmitrovsky E.
    \nMol Cancer Ther<\/span>. 2016 Nov;15(11):2758-2766. Epub 2016 Aug 22.
    \nPMID: 27550941 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  14. G0S2 Suppresses Oncogenic Transformation by Repressing a MYC-Regulated Transcriptional Program.<\/a>
    \nYim CY, Sekula DJ, Hever-Jardine MP, Liu X, Warzecha JM, Tam J, Freemantle SJ, Dmitrovsky E, Spinella MJ.
    \nCancer Res<\/span>. 2016 Mar 1;76(5):1204-13. doi: 10.1158\/0008-5472.CAN-15-2265. Epub 2016 Feb 2.
    \nPMID: 26837760 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  15. Mice null for the deubiquitinase USP18 spontaneously develop leiomyosarcomas.<\/a>
    \nChinyengetere F, Sekula DJ, Lu Y, Giustini AJ, Sanglikar A, Kawakami M, Ma T, Burkett SS, Eisenberg BL, Wells WA, Hoopes PJ, Demicco EG, Lazar AJ, Torres KE, Memoli V, Freemantle SJ, Dmitrovsky E.
    \nBMC Cancer<\/span>. 2015 Nov 10;15:886. doi: 10.1186\/s12885-015-1883-8.
    \nPMID: 26555296 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  16. Effective capture of circulating tumor cells from a transgenic mouse lung cancer model using dendrimer surfaces immobilized with anti-EGFR.<\/a>
    \nMyung JH, Roengvoraphoj M, Tam KA, Ma T, Memoli VA, Dmitrovsky E, Freemantle SJ, Hong S.
    \nAnal Chem<\/span>. 2015 Oct 6;87(19):10096-102. doi: 10.1021\/acs.analchem.5b02766. Epub 2015 Sep 10.
    \nPMID: 26312815 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  17. All-trans-retinoic acid antagonizes the Hedgehog pathway by inducing patched.<\/a>
    \nBusch AM, Galimberti F, Nehls KE, Roengvoraphoj M, Sekula D, Li B, Guo Y, Direnzo J, Fiering SN, Spinella MJ, Robbins DJ, Memoli VA, Freemantle SJ, Dmitrovsky E.
    \nCancer Biol Ther<\/span>. 2014 Apr;15(4):463-72. doi: 10.4161\/cbt.27821. Epub 2014 Feb 4.
    \nPMID: 24496080 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  18. Comparing histone deacetylase inhibitor responses in genetically engineered mouse lung cancer models and a window of opportunity trial in patients with lung cancer.<\/a>
    \nMa T, Galimberti F, Erkmen CP, Memoli V, Chinyengetere F, Sempere L, Beumer JH, Anyang BN, Nugent W, Johnstone D, Tsongalis GJ, Kurie JM, Li H, Direnzo J, Guo Y, Freemantle SJ, Dragnev KH, Dmitrovsky E.
    \nMol Cancer Ther<\/span>. 2013 Aug;12(8):1545-55. doi: 10.1158\/1535-7163.MCT-12-0933. Epub 2013 May 16.
    \nPMID: 23686769 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  19. Evidence for tankyrases as antineoplastic targets in lung cancer.<\/a>
    \nBusch AM, Johnson KC, Stan RV, Sanglikar A, Ahmed Y, Dmitrovsky E, Freemantle SJ.
    \nBMC Cancer<\/span>. 2013 Apr 28;13:211. doi: 10.1186\/1471-2407-13-211.
    \nPMID: 23621985 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  20. Repression of exogenous gene expression by the retinoic acid target gene G0S2.<\/a>
    \nMa T, Dong JP, Sekula DJ, Fei DL, Lamph WW, Henderson M, Lu Y, Blumen S, Freemantle SJ, Dmitrovsky E.
    \nInt J Oncol<\/span>. 2013 May;42(5):1743-53. doi: 10.3892\/ijo.2013.1876. Epub 2013 Mar 28.
    \nPMID: 23546556 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  21. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.<\/a>
    \nGalimberti F, Busch AM, Chinyengetere F, Ma T, Sekula D, Memoli VA, Dragnev KH, Liu F, Johnson KC, Guo Y, Freemantle SJ, Andrew AS, Greninger P, Robbins DJ, Settleman J, Benes C, Dmitrovsky E.
    \nInt J Oncol<\/span>. 2012 Nov;41(5):1751-61. doi: 10.3892\/ijo.2012.1599. Epub 2012 Aug 22.
    \nPMID: 22923130 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  22. Evidence for the ubiquitin protease UBP43 as an antineoplastic target.<\/a>
    \nGuo Y, Chinyengetere F, Dolinko AV, Lopez-Aguiar A, Lu Y, Galimberti F, Ma T, Feng Q, Sekula D, Freemantle SJ, Andrew AS, Memoli V, Dmitrovsky E.
    \nMol Cancer Ther<\/span>. 2012 Sep;11(9):1968-77. doi: 10.1158\/1535-7163.MCT-12-0248. Epub 2012 Jul 2.
    \nPMID: 22752428 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
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  23. Bexarotene plus erlotinib suppress lung carcinogenesis independent of KRAS mutations in two clinical trials and transgenic models.<\/a>
    \nDragnev KH, Ma T, Cyrus J, Galimberti F, Memoli V, Busch AM, Tsongalis GJ, Seltzer M, Johnstone D, Erkmen CP, Nugent W, Rigas JR, Liu X, Freemantle SJ, Kurie JM, Waxman S, Dmitrovsky E.
    \nCancer Prev Res (Phila)<\/span>. 2011 Jun;4(6):818-28. doi: 10.1158\/1940-6207.CAPR-10-0376.
    \nPMID: 21636548 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  24. Serine\/threonine kinase 17A is a novel p53 target gene and modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells.<\/a>
    \nMao P, Hever MP, Niemaszyk LM, Haghkerdar JM, Yanco EG, Desai D, Beyrouthy MJ, Kerley-Hamilton JS, Freemantle SJ, Spinella MJ.
    \nJ Biol Chem<\/span>. 2011 Jun 3;286(22):19381-91. doi: 10.1074\/jbc.M111.218040. Epub 2011 Apr 13.
    \nPMID: 21489989 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  25. Involvement of microRNAs in lung cancer biology and therapy.<\/a>
    \nLiu X, Sempere LF, Guo Y, Korc M, Kauppinen S, Freemantle SJ, Dmitrovsky E.
    \nTransl Res<\/span>. 2011 Apr;157(4):200-8. doi: 10.1016\/j.trsl.2011.01.001. Epub 2011 Feb 4. Review.
    \nPMID: 21420030 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  26. Cyclin E transgenic mice: discovery tools for lung cancer biology, therapy, and prevention.<\/a>
    \nFreemantle SJ, Dmitrovsky E.
    \nCancer Prev Res (Phila)<\/span>. 2010 Dec;3(12):1513-8. doi: 10.1158\/1940-6207.CAPR-10-0297. Review.
    \nPMID: 21149327 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  27. MicroRNA-31 functions as an oncogenic microRNA in mouse and human lung cancer cells by repressing specific tumor suppressors.<\/a>
    \nLiu X, Sempere LF, Ouyang H, Memoli VA, Andrew AS, Luo Y, Demidenko E, Korc M, Shi W, Preis M, Dragnev KH, Li H, Direnzo J, Bak M, Freemantle SJ, Kauppinen S, Dmitrovsky E.
    \nJ Clin Invest<\/span>. 2010 Apr;120(4):1298-309. doi: 10.1172\/JCI39566. Epub 2010 Mar 8.
    \nPMID: 20237410 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  28. High DNA methyltransferase 3B expression mediates 5-aza-deoxycytidine hypersensitivity in testicular germ cell tumors.<\/a>
    \nBeyrouthy MJ, Garner KM, Hever MP, Freemantle SJ, Eastman A, Dmitrovsky E, Spinella MJ.
    \nCancer Res<\/span>. 2009 Dec 15;69(24):9360-6. doi: 10.1158\/0008-5472.CAN-09-1490.
    \nPMID: 19951990 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  29. Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting.<\/a>
    \nSnow GE, Kasper AC, Busch AM, Schwarz E, Ewings KE, Bee T, Spinella MJ, Dmitrovsky E, Freemantle SJ.
    \nBMC Cancer<\/span>. 2009 Oct 29;9:383. doi: 10.1186\/1471-2407-9-383.
    \nPMID: 19874621 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  30. Retinoic acid mediates long-paced oscillations in retinoid receptor activity: evidence for a potential role for RIP140.<\/a>
    \nHeim KC, Gamsby JJ, Hever MP, Freemantle SJ, Loros JJ, Dunlap JC, Spinella MJ.
    \nPLoS One<\/span>. 2009 Oct 28;4(10):e7639. doi: 10.1371\/journal.pone.0007639.
    \nPMID: 19862326 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  31. Uncovering growth-suppressive MicroRNAs in lung cancer.<\/a>
    \nLiu X, Sempere LF, Galimberti F, Freemantle SJ, Black C, Dragnev KH, Ma Y, Fiering S, Memoli V, Li H, DiRenzo J, Korc M, Cole CN, Bak M, Kauppinen S, Dmitrovsky E.
    \nClin Cancer Res<\/span>. 2009 Feb 15;15(4):1177-83. doi: 10.1158\/1078-0432.CCR-08-1355.
    \nPMID: 19228723 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
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  32. Retinoid chemoprevention trials: cyclin D1 in the crosshairs.<\/a>
    \nFreemantle SJ, Guo Y, Dmitrovsky E.
    \nCancer Prev Res (Phila)<\/span>. 2009 Jan;2(1):3-6. doi: 10.1158\/1940-6207.CAPR-08-0218. Review. No abstract available.
    \nPMID: 19139010 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  33. UBE1L represses PML\/RAR by targeting the PML domain for ISG15ylation.<\/a>
    \nShah SJ, Blumen S, Pitha-Rowe I, Kitareewan S, Freemantle SJ, Feng Q, Dmitrovsky E.
    \nMol Cancer Ther<\/span>. 2008 Apr;7(4):905-14. doi: 10.1158\/1535-7163.MCT-07-0515.
    \nPMID: 18413804 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
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  34. Selective repression of retinoic acid target genes by RIP140 during induced tumor cell differentiation of pluripotent human embryonal carcinoma cells.<\/a>
    \nHeim KC, White KA, Deng D, Tomlinson CR, Moore JH, Freemantle SJ, Spinella MJ.
    \nMol Cancer<\/span>. 2007 Sep 19;6:57.
    \nPMID: 17880687 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  35. Cyclin degradation for cancer therapy and chemoprevention.<\/a>
    \nFreemantle SJ, Liu X, Feng Q, Galimberti F, Blumen S, Sekula D, Kitareewan S, Dragnev KH, Dmitrovsky E.
    \nJ Cell Biochem<\/span>. 2007 Nov 1;102(4):869-77. Review.
    \nPMID: 17868090 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  36. The direct p53 target gene, FLJ11259\/DRAM, is a member of a novel family of transmembrane proteins.<\/a>
    \nKerley-Hamilton JS, Pike AM, Hutchinson JA, Freemantle SJ, Spinella MJ.
    \nBiochim Biophys Acta<\/span>. 2007 Apr;1769(4):209-19. Epub 2007 Feb 22.
    \nPMID: 17397945 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  37. Transgenic cyclin E triggers dysplasia and multiple pulmonary adenocarcinomas.<\/a>
    \nMa Y, Fiering S, Black C, Liu X, Yuan Z, Memoli VA, Robbins DJ, Bentley HA, Tsongalis GJ, Demidenko E, Freemantle SJ, Dmitrovsky E.
    \nProc Natl Acad Sci U S A<\/span>. 2007 Mar 6;104(10):4089-94. Epub 2007 Feb 27.
    \nPMID: 17360482 [PubMed \u2013 indexed for MEDLINE] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  38. Uncovering residues that regulate cyclin D1 proteasomal degradation.<\/a>
    \nFeng Q, Sekula D, M\u00fcller R, Freemantle SJ, Dmitrovsky E.
    \nOncogene<\/span>. 2007 Aug 2;26(35):5098-106. Epub 2007 Feb 19.
    \nPMID: 17310991 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  39. Repression of cyclin D1 as a target for germ cell tumors.<\/a>
    \nFreemantle SJ, Vaseva AV, Ewings KE, Bee T, Krizan KA, Kelley MR, Hattab EM, Memoli VA, Black CC, Spinella MJ, Dmitrovsky E.
    \nInt J Oncol<\/span>. 2007 Feb;30(2):333-40.
    \nPMID: 17203214 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  40. Testicular Germ Cell Tumors: A Paradigm for the Successful Treatment of Solid Tumor Stem Cells.<\/a>
    \nGiuliano CJ, Freemantle SJ, Spinella MJ.
    \nCurr Cancer Ther Rev<\/span>. 2006 Aug 1;2(3):255-270.
    \nPMID: 24482633 [PubMed] Free PMC Article
    \n    Similar articles<\/a><\/li>\n
  41. The retinoic acid paradox in cancer chemoprevention.<\/a>
    \nFreemantle SJ, Dragnev KH, Dmitrovsky E.
    \nJ Natl Cancer Inst<\/span>. 2006 Apr 5;98(7):426-7. No abstract available.
    \nPMID: 16595769 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  42. A novel retinoic acid receptor beta isoform and retinoid resistance in lung carcinogenesis.<\/a>
    \nPetty WJ, Li N, Biddle A, Bounds R, Nitkin C, Ma Y, Dragnev KH, Freemantle SJ, Dmitrovsky E.
    \nJ Natl Cancer Inst<\/span>. 2005 Nov 16;97(22):1645-51.
    \nPMID: 16288117 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  43. Retinoic acid represses a cassette of candidate pluripotency chromosome 12p genes during induced loss of human embryonal carcinoma tumorigenicity.<\/a>
    \nGiuliano CJ, Kerley-Hamilton JS, Bee T, Freemantle SJ, Manickaratnam R, Dmitrovsky E, Spinella MJ.
    \nBiochim Biophys Acta<\/span>. 2005 Oct 15;1731(1):48-56. Epub 2005 Sep 1.
    \nPMID: 16168501 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  44. Retinoid targeting of different D-type cyclins through distinct chemopreventive mechanisms.<\/a>
    \nMa Y, Feng Q, Sekula D, Diehl JA, Freemantle SJ, Dmitrovsky E.
    \nCancer Res<\/span>. 2005 Jul 15;65(14):6476-83.
    \nPMID: 16024653 [PubMed \u2013 indexed for MEDLINE] Free Article
    \n    Similar articles<\/a><\/li>\n
  45. Specific chemopreventive agents trigger proteasomal degradation of G1 cyclins: implications for combination therapy.<\/a>
    \nDragnev KH, Pitha-Rowe I, Ma Y, Petty WJ, Sekula D, Murphy B, Rendi M, Suh N, Desai NB, Sporn MB, Freemantle SJ, Dmitrovsky E.
    \nClin Cancer Res<\/span>. 2004 Apr 1;10(7):2570-7.
    \nPMID: 15073138 [PubMed \u2013 indexed for MEDLINE] Free Article
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  46. Retinoids in cancer therapy and chemoprevention: promise meets resistance.<\/a>
    \nFreemantle SJ, Spinella MJ, Dmitrovsky E.
    \nOncogene<\/span>. 2003 Oct 20;22(47):7305-15. Review.
    \nPMID: 14576840 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  47. Negative feedback at the level of nuclear receptor coregulation. Self-limitation of retinoid signaling by RIP140.<\/a>
    \nWhite KA, Yore MM, Warburton SL, Vaseva AV, Rieder E, Freemantle SJ, Spinella MJ.
    \nJ Biol Chem<\/span>. 2003 Nov 7;278(45):43889-92. Epub 2003 Sep 22.
    \nPMID: 14506269 [PubMed \u2013 indexed for MEDLINE] Free Article
    \n    Similar articles<\/a><\/li>\n
  48. Microarray analysis uncovers retinoid targets in human bronchial epithelial cells.<\/a>
    \nMa Y, Koza-Taylor PH, DiMattia DA, Hames L, Fu H, Dragnev KH, Turi T, Beebe JS, Freemantle SJ, Dmitrovsky E.
    \nOncogene<\/span>. 2003 Jul 31;22(31):4924-32.
    \nPMID: 12894236 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  49. Characterization and tissue-specific expression of human GSK-3-binding proteins FRAT1 and FRAT2.<\/a>
    \nFreemantle SJ, Portland HB, Ewings K, Dmitrovsky F, DiPetrillo K, Spinella MJ, Dmitrovsky E.
    \nGene<\/span>. 2002 May 29;291(1-2):17-27.
    \nPMID: 12095675 [PubMed \u2013 indexed for MEDLINE]\n    Similar articles<\/a><\/li>\n
  50. Developmentally-related candidate retinoic acid target genes regulated early during neuronal differentiation of human embryonal carcinoma.<\/a>
    \nFreemantle SJ, Kerley JS, Olsen SL, Gross RH, Spinella MJ.
    \nOncogene<\/span>. 2002 Apr 25;21(18):2880-9.
    \nPMID: 11973648 [PubMed \u2013 indexed for MEDLINE] Free Article
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  51. UBE1L is a retinoid target that triggers PML\/RARalpha degradation and apoptosis in acute promyelocytic leukemia.<\/a>
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