Department of Biochemistry
“Our previous research focused on mechanisms of steroid receptor action at the transcriptional and posttranscriptional levels. In calendar year 2012, we described novel small molecule inhibitors of androgen receptor (AR), estrogen receptor (ER) and progesterone receptor (PR). These small molecules are new probes for key pathways in prostate cancer, and breast, ovarian and endometrial cancer, and are being evaluated as potential anticancer drugs.”
Visit David Shapiro's Lab website.
- Drug screening
- Fluorescence anisotropy microplate assay (FAMA)
- quantitative chromatin immunoprecipitation (ChIP)