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Hsiao, Shih-Hsuan

Clinical Assistant Professor, Veterinary Diagnostic Laboratory
Clinical Assistant Professor, Veterinary Clinical Medicine

Address and Contact Information

2001 S. Lincoln Ave.
1227 VMBSB
2001 S Lincoln
Urbana, IL  61802


  • PhD in Veterinary Pathobiology, University of Illinois, 2005
  • MS, National Taiwan University, Taiwan, 1996
  • DVM, National Taiwan University, Taiwan, 1994

Research Interests

Pathophysiology and signaling pathways of sphingolipids, especially their roles in fumonisin mycotoxicosis and tumor necrosis factor α induced cardiovascular dysfunction in swine.


Dr. Hsiao, also known as Vincent, re-jointed the University of Illinois Veterinary Diagnostic Laboratory as an anatomic pathologist in 2011. He is a veterinary graduate of National Taiwan University in Taiwan. He completed his PhD/residency training program in our Pathobiology Department in 2005 and remained at the Diagnostic Laboratory as a diagnostic pathologist till 2007. Vincent returned to Taiwan to accept an Assistant Professor position at National Chia-Yi University and, in 2008, National Taiwan University specializing in farm animal medicine. During that time, his research focused mostly on bovine mastitis, bovine tuberculosis, paratuberculosis, caprine arthritis-encephalitis and porcine respiratory disease complex working towards developing herd-based and national-level control strategies against the diseases. He currently provides diagnostic services for food, companion, zoo and laboratory animal clients with a special interest in toxicologic diseases.

Courses Taught

VM601 & 606 Clinical Practice - Diagnostic Medicine

VM608 Pathobiology - Endocrine Pathology

VM612-616 Clinical Year Rotation - Diagnostic Medicine

PATH 545 Veterinary Diagnostic Pathology

PATH 547 Pathology Seminar

PATH 559 Surgical Pathology

Selected Publications

Grimmer ED, Canisso IF, Hsiao SH, Garrett EF. (2017). Squamous cell carcinoma and papilloma virus in the prepuce of a Boer buck. Clinical Theriogenology. 9(4): 595-599.

Moore AR, Hsiao SH, Chu CT, Aldridge BM, Schnelle AN. (2017). Pathology in Practice: Thrombotic meningoencephalitis (TME) in a calf. J Am Vet Med Assoc. 251(6): 665-668.

Lindemann DM, Allender MC, Rzadkowska M, Archer G, Kane L, Baitchman E, Driskell EA, Chu CT, Singh K, Hsiao SH, Sykes JM 4th, Cox S. (2017) Pharmacokinetics, efficacy, and safety of voriconazole and itraconazole in healthy cottonmouths (agkistrodon piscivorus) and massasauga rattlesnakes (sistrurus catenatus) with snake fungal disease. J Zoo Wildl Med. 48(3):757-766.

Rosser MF, Lindemann DM, Barger AM, Allender MC, Hsiao SH, Howes ME. (2016). Systemic blastomycosis in a captive red ruffed lemur (varecia rubra). J Zoo Wildl Med. 47(3):912-916.

Rosenhagen N, Whittington JK, Hsiao SH. (2016). Infiltrative Spinal Lipoma in a Canada Goose (Branta canadensis). J Avian Med Surg. 30(1):60-5.

Dolinski AC, Allender MC, Hsiao V, Maddox CW. (2014). Systemic Ophidiomyces ophiodiicola infection in a free-ranging plains garter snake (Thamnophis radix). Journal of Herpetological Medicine and Surgery. 24(1-2): 7-10.

Tsai YC, Jeng CR, Chang CC, Hsiao SH, Chang HW, Lin CM, Chia MY, Wan CH, Pang VF. (2014). Differences in the expression of innate immune response-modulating genes in blood monocytes between subclinically porcine circovirus type 2 (PCV2)-infected and PCV2-free pigs prior to and after lipopolysaccharide stimulation in vitro. Taiwan Veterinary Journal 40: 37-48.

Shanaman MM, Mitchell MA, Haskins S, Welle K, Demeter Z, Hsiao SH, Murrell-Ritter S, O’Brien RT, (2012). Diagnostic Challenge. Journal of Exotic Pet Medicine 21: 264–269.

Lin CM, Jeng CR, Hsiao SH, Lee Y, Tsai YC, Chia MY, Pang VF. (2012). Monocyte-derived dendritic cells enhance cell proliferation and porcine circovirus type 2 replication in concanavalin A-stimulated swine peripheral blood lymphocytes in vitro. Vet Immunol Immunopathol. 145: 368-378.

Wang C, Pang VF, Jeng CR, Lee F, Huang YW, Lin YL, Hsiao SH, Lai SS. (2011). Detection of porcine circovirus type 1 in commercial porcine vaccines by loop-mediated isothermal amplification. Folia Microbiol (Praha) 56:483-9.

Chia MY, Hsiao SH, Chan HT, Do YY, Huang PL, Chang HW, Tsai YC, Lin CM, Pang VF, Jeng CR. (2011). Evaluation of the immunogenicity of a transgenic tobacco plant expressing the recombinant fusion protein of GP5 of porcine reproductive and respiratory syndrome virus and B subunit of Escherichia coli heat-labile enterotoxin in pigs. Vet Immunol Immunopathol. 140:215-25.

Lin CM, Jeng CR, Hsiao SH, Liu JP, Chang CC, Chiou MT, Tsai YC, Chia MY, Pang VF. (2011). Immunopathological characterization of porcine circovirus type 2 infection-associated follicular changes in inguinal lymph nodes using high-throughput tissue microarray. Vet Microbiol. 149: 72-84.

Chia MY, Hsiao SH, Chan HT, Do YY, Huang PL, Chang HW, Tsai YC, Lin CM, Cheng CH, Pang VF, Jeng CR. (2011). Improved Immunogenicity of DNA Constructs Co-expressing the GP5 and M Proteins of Porcine Reproductive and Respiratory Syndrome Virus by Glycine-proline-glycine-proline (GPGP) Linker in Mice. Taiwan Veterinary Journal 37: 12-23.

Chia MY, Hsiao SH, Chan HT, Do YY, Huang PL, Chang HW, Tsai YC, Lin CM, Pang VF, Jeng CR. (2010). The immunogenicity of DNA constructs co-expressing GP5 and M proteins of porcine reproductive and respiratory syndrome virus conjugated by GPGP linker in pigs. Vet Microbiol. 146: 189-99.

Tsai YC, Jeng CR, Hsiao SH, Chang HW, Liu JJ, Chang CC, Lin CM, Chia MY, Pang VF. (2010). Porcine circovirus type 2 (PCV2) induces cell proliferation, fusion, and chemokine expression in swine monocytic cells in vitro. Vet Res. 41: 60.

Chia MY, Hsiao SH, Chan HT, Do YY, Huang PL, Chang HW, Tsai YC, Lin CM, Pang VF, Jeng CR. (2010). Immunogenicity of recombinant GP5 protein of porcine reproductive and respiratory syndrome virus expressed in tobacco plant. Vet Immunol Immunopathol. 135: 234-42.

Yang SF, Yang HL, Hsiao SH, Lin PC, Cheing BH, Tsai HP, Fan CL, Wang WL, Chang CC, Liang SL. (2010). Case Report: Percutaneous Transvenous Coil Embolization of an Extrahepatic Portosystemic Shunt in a Dog. Taiwan Veterinary Journal 36:107-114.

Lin CM, Jeng CR, Hsiao SH, Chang CC, Liu CH, Tsai YC, Chia MY, Pang VF. (2009). Development and evaluation of an indirect in situ polymerase chain reaction for the detection of porcine circovirus type 2 in formalin-fixed and paraffin-embedded tissue specimens. Vet Microbiol. 138:225-34. 

Chia MY, Jeng CR, Hsiao SH, Lee AH, Chen CY, Pang VF. (2009). Entamoeba invadens myositis in a common water monitor lizard (Varanus salvator). Vet Pathol. 46:673-6.

Hsiao SH, Tumbleson ME, Constable PD, Haschek WM. (2007). Use of formalin-fixed tissues to determine fumonisin B1-induced sphingolipid alterations in swine. Journal of Veterinary Diagnostic Investigations 19(4):425-430.

Adkesson MJ, Gorman ME, Hsiao V, Whittington JK, Langan JN.    (2007). Toxoplasma gondii inclusions in peripheral blood leukocytes of a red-necked wallaby (Macropus rufogriseus). Veterinary Clinical Pathology 36(1):97-100.

Hsiao SH, Constable PD, Smith GW, Haschek WM.  (2005). Effects of exogenous sphinganine, sphingosine, and sphingosine-1-phosphate on relaxation and contraction of porcine thoracic aortic and pulmonary arterial rings. Toxicological Sciences 86(1):194-199.

Honors and Awards

Teachers Ranked as Excellent by their Students, 2012, 2013, 2014, 2015, 2016 & 2017, University of Illinois

Outstanding Faculty of the Year, 2007, National Chia-Yi University, Taiwan

Edward W. and Lois G. Voss All Around Excellence Award, 2005, University of Illinois

Student Travel Award, 2005, Society of Toxicologic Pathology 24th Annual Symposium

Outstanding Poster Presentation, 2005, Mu Chapter of Phi Zeta

Frank C. Lu Award, 2005, Food Safety Special Section of the Society of Toxicology

LDAP Details for Hsiao, Shih-Hsuan