Contemporary Issues in Target Organ Toxicology Pathology:
Hepatobiliary and Cardiovascular Systems
This course is designed for pathologists and other professionals working in toxicology-related fields such as the pharmaceutical, chemical, consumer, and environmental areas. The objective of the course is to provide an understanding of the basis and manifestations of target organ responses to xenobiotic injury and thus enhance attendees’ skills in interpreting pathology data.
Course Check-In
All course sessions will be held at the Hilton Garden Inn. Course check-in will be available on Wednesday, July 22, 2009, between 11:30 a.m. and 1:15 p.m.
Wednesday, July 22, 2009
| 11:30 a.m.-1:15 p.m. | Course Check-In Lunch |
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| 1:15-1:30 p.m. | Welcome and Introduction Wanda Haschek-Hock, University of Illinois at Urbana-Champaign |
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| Hepatobiliary System | ||
| 1:30-2:00 p.m. | Issues in Drug-Induced Hepatotoxicity James A. Popp, Stratoxon LLC Topic Section Chair |
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| 2:00-3:00 p.m. | Hepatic Response to Toxic Injury John M. Cullen, North Carolina State University |
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| 3:00-3:30 p.m. | Break | |
| 3:30-4:15 p.m. | Hepatic Response to Injury (continued) John M. Cullen, North Carolina State University |
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| 4:15-5:00 p.m. | Background Lesions and Nomenclature Robert R. Maronpot, Maronpot Consulting, LLC |
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| 5:45 p.m. | Reception | |
| 6:30 p.m. | Dinner at Hilton Garden Inn | |
Thursday, July 23, 2009
| Hepatobiliary System (continued) | ||
| 7:00-8:00 a.m. | Continental Breakfast | |
| 8:00-9:00 a.m. | Clinical Pathology Philip F. Solter, University of Illinois at Urbana-Champaign |
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| 9:00-10:00 a.m. | Hepatic Effects of Drug Metabolizing Enzyme Induction Daniela Ennulat, GlaxoSmithKline |
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| 10:00-10:30 a.m. | Break | |
| 10:30-11:30 a.m.. | Genomics of Liver Toxicity and Carcinogenesis David E. Malarkey, national Institute of Environmental Health Sciences |
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| 11:30 a.m.-12:00 p.m. | Drug-Induced Hepatotoxicity: Final Thoughts James A. Popp, Stratoxon LLC |
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| 12:00- 1:15 p.m | Lunch | |
| Cardiovascular System | ||
| 1:15-2:00 p.m. | Issues in Drug-Induced Cardiovascular Toxicity Brian R. Berridge, GlaxoSmithKline Topic Section Chair |
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| 2:00-3:00 p.m. | Cardiovascular Response to Toxic Injury John F. VanVleet, Purdue University |
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| 3:00-3:30 p.m. | Break | |
| 3:30-5:00 p.m. | Cardiovascular Response to Toxic Injury (continued) John F. VanVleet, Purdue University |
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| 5:30 p.m. | Depart for Dinner and Tour | |
| 5:45 p.m. | Tour of University of Illinois College of Veterinary Medicine Pathology Facilities | |
| 6:30 p.m. | Dinner at Alto Vineyards | |
Friday, July 24, 2009
| Cardiovascular System (continued) | ||
| 7:00-8:00 a.m. | Continental Breakfast | |
| 8:00-9:00 a.m. | Drug-Induced Vascular Injury Heath C. Thomas, GlaxoSmithKline |
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| 9:00-10:00 a.m. | Drug-Induced Valvulopathy Chandikumar S. Elangbam, GlaxoSmithKline |
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| 10:00-10:30 a.m. | Break | |
| 10:30-11:30 a.m. . | Biomarkers of Cardiovascular Toxicity Philip F. Solter, University of Illinois at Urbana-Champaign |
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| 11:30 a.m.-12:00 p.m. . | Drug-Induced Cardiovascular Toxicity: Final Thoughts Brian R. Berridge, GlaxoSmithKline |
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| 12:00 p.m. | Adjourn and Lunch | |