Generation of transgenic animal models

Reproductive organsOur lab generates genetically modified (or transgenic) animal models. Genomic DNA sequences are modified using a variety of genetic manipulation procedures in vitro. The DNA sequences are then introduced into the genomes of recipient animals, creating new animals that never existed before. New animal models are continuously generated and used in our laboratory. Shown are the microscopic images taken from newly generated transgenic mouse in which estrogen response tissues automatically labeled in blue color. Show are the male reproductive organs (top panel), female reproductive organs (middle) and ventral side of the male brain (bottom).