The following faculty, listed alphabetically, participate in the Interdisciplinary Toxicology program by teaching courses that meet program requirements, engaging in research on toxicology-related subjects, advising graduate students, and participating in a variety of program activities on a voluntary basis. Names and photos are linked to corresponding webpages.
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Indrani Bagchi
Department of Comparative Biosciences |
| Molecular and cellular basis of implantation and study of natural and synthetic endocrine regulators that control this process. |
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Milan Bagchi
Department of Molecular and Integrative Physiology |
| Mechanisms of gene regulation by steroid and thyroid hormone receptors: molecular basis of tissue specific actions of estrogen receptor modulators (SERMs) and other synthetic steroid receptor agonists and antagonists. |
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Janice M. Bahr
Professor Emeritus
Department of Animal Sciences |
| Role of hormones and environmental estrogens in regulating the function of the reproductive tract in males and females. |
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Stephen A. Boppart
Depts. of Electrical and Computer Engineering, Bioengineering, and Medicine |
| Imaging and tracking of nanoparticles and microparticles within living systems; biodistribution and biological effects of exogenous contrast agents; multi-modal imaging of cancer. |
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Val R. Beasley
Department of Comparative Biosciences |
| Ecosystem health; ecotoxicological effects of pesticides, metals, industrial contaminants and natural toxins; factors that contribute to declining amphibian populations. |
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May R. Berenbaum
Department of Entomology |
| Mode of action of plant-derived toxins and mechanisms of detoxification in herbivorous insects. |
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Aditi Das
Department of Comparative Biosciences; Affiliate, Department of Biochemistry &
Beckman Institute for Advanced Science & Technology
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Drug metabolism and toxicity by cytochrome P450s; effect of polymorphisms on functional activity;
Eicosanoid synthesizing membrane proteins involved in inflammation; Cardiovascular health and hypertension; Nanotechnology to probe drug binding to membrane proteins.
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Levent Dirikolu
Department of Comparative Biosciences |
| Therapeutic and toxic agents in animals; pharmacokinetics, pharmacodynamics, toxicokinetics; molecular, clinical and analytical pharmacology/toxicology. |
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Timothy M. Fan
Department of Veterinary Clinical Medicine |
| Study of novel agents and their associated efficacy and toxicity for the treatment of spontaneously-arising tumors in companion animals. |
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Duncan C. Ferguson
Department of Comparative Biosciences |
| Comparative thyroid physiology and pharmacology; comparative pharmacology; environmental thyroid disruptors; role of thyroid hormone in neurodevelopment. |
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Jodi A. Flaws
Department of Comparative Biosciences |
| Effect of environmental chemicals on development and function of the mamamalian ovary. |
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Bettina M. Francis
Department of Entomology and Comparative Biosciences |
| Developmental toxicology; gene expression in mammalian organogenesis and its perturbation by xenobiotics; pesticide toxicology; ecotoxicology. |
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Gregory G. Freund
Depts. of Pathology, College of Medicine and Animal Sciences |
Neuroimmune and immunobehavioral complications of diabesity and a
high-fat diet. |
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Wanda M. Haschek-Hock
Professor Emeritus
Department of Pathobiology |
| Toxicologic pathology; mycotoxicoses, pathogenesis of fumonisin toxicity; pathology of laboratory and genetically engineered animals. |
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William G. Helferich
Department of Food Science and Human Nutrition |
| Food safety and toxicology; anti-toxicant action of chemicals in foods with emphasis on phytochemicals which alter the progression of breast cancer. |
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Edwin E. Herricks
Department of Civil Engineering |
| Time scales of toxic response; effects of containments and other environmental alterations on organisms, populations and communities with an emphasis on aquatic ecosystems, improvement of engineering design and environmental decision-making. |
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Rex A. Hess
Professor Emeritus
Department of Comparative Biosciences |
| Male reproductive biology and toxicology; mechanisms that cause infertility in males; estrogens and anti-estrogens in the male. |
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Marie-Claude Hofmann
Department of Comparative Biosciences |
| Toxicity of nanomaterials in the male germ line. Disruption of the speramatogonial stem cell niche and signaling pathways in testicular cancer. |
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Elizabeth H. Jeffrey
Depts. of Food Science and Human Nutrition, Pharmacology, Comparative Biosciences and Nutritional Sciences |
| Diet and cancer; mechanisms for bioactivation and detoxification of toxic and carcinogenic chemicals; safety and efficacy of bioactive food components and dietary supplements. |
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Janice M. Juraska
Department of Psychology and Neuroscience Program |
| Hormonal influences in neuronal structure in cognitive parts of the rat brain, such as the cerebral cortex, corpus callosum and hippocampus. Current emphasis is on adolescence/puberty and aging. |
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Benita S. Katzenellenbogen
Departments of Molecular & Integrative Physiology, and Cell & Developmental Biology |
| Regulation of gene expression, signal transduction, and cell proliferation by hormones, environmental toxicants, and growth factors; mechanisms of hormone, antihormone and nuclear receptor actions in normal and cancer cells. |
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John A. Katzenellenbogen
Department of Chemistry |
| Organic synthesis; steroid hormone structure and activity; steroid hormone receptor structure and function; estrogens and phytoestrogens. |
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Byron W. Kemper
Depts. of Pharmacology, Molecular & Integrative Physiology, and Cell & Structural Biology |
| Regulation of P450 gene expression by phenobarbital; structural determinants of microsomal membrane-bound P450s for targeting to the endoplasmic reticulum, folding, membrane interactions and substrate interactions. |
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Donna L. Korol
Depts. of Psychology, Neuroscience Program and Institute for Genomic Biology |
| Neural mechanisms of cognitive aging, focusing on the impact of endogenous estrogens, phytoestrogens, and exercise in health and disease. |
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Sidonie N. Lavergne
Department of Comparative Biosciences |
| Humoral and cellular markers of drug-induced allergy; relationship between immunity (peripheral & central) and sickness behaviors (depression). |
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Jeffrey M. Levengood
Department of Comparative Biosciences |
| Ecological correlates of contaminant exposure in wildlife; contaminant-disease interactions in wildlife; landscape ecotoxicology. |
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Elvira de Mejia
Department of Food Science and Human Nutrition |
| Mechanisms of action of bioactive components in food proteins and flavanoids related to the prevention of cancer. |
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Ann Nardulli
Department of Molecular and Integrative Physiology |
| Mechanisms by which pharmacologic agents modulate estrogen receptor activity and expression of estrogen-responsive genes. |
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Romana Nowak
Department of Animal Sciences |
| Pathogenesis of endometriosis and uterine fibroids, growth factor expression in the uterus, and development of these diseases. |
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Michael J. Plewa
Departments of Crop Sciences and Microbiology |
| Environmental and molecular mutagenesis, genetic toxicology and toxicogenomics. |
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Lori Raetzman
Department of Molecular and Integrative Physiology and Neuroscience Program |
| Signaling pathways directing development of the pituitary gland and impact of environmental toxicants on pituitary cell differentiation and function. |
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Lane Rayburn
Department of Crop Sciences |
| Use of molecular and flow cytogenetics to study the effects of environmental mutagens on genome organization. |
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Karin Rosenblatt
Department of Community Health |
| Cancer of epidemiology (particularly gynecologic cancers) including investigations of genital talc exposure and electromagnetic field exposures. |
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Marilyn Ruiz
Department of Pathobiology |
| Ecological toxicology; spatial analysis and visualization to better understand and model the complex interface between humans and animals and environmental exposure to toxins. |
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Susan L. Schantz (Chair)
Departments of Comparative Biosciences and Psychology, and Neuroscience Program |
| Neurotoxicology; nervous system effects of environmental chemicals during development and aging. |
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Mary A. Schuler
Departments of Cell and Developmental Biology, Plant Biology, and Biochemistry |
| Plant P450 monooxygenases involved in herbicide detoxification and insect P450 monooxygenases involved in plant allelochemicals in insecticide metabolism. |
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Mariangela Segre
Department of Pathobiology |
| Regulation of antibody formation, effect of aging and diet restriction on the immune system, effects of PCBs on immunologic and physiologic parameters, and development of cocaine antogonistic peptides. |
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Douglas G. Simpson
Department of Statistics |
| Applied statistics; environmental statistics; combining information from multiple sources in toxicological risk assessment. |
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Keith W. Singletary
Department of Food Science and Human Nutrition |
| Cancer chemoprevention: identifying bioactive phytochemicals from fruits, vegetables, and herbs as anticarcinogens and determining their molecular mechanisms of action; determining molecular basis for the enhancement of breast cancer by ethanol. |
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David J. Soucek
Departments of Entomology and Natural Resources and Environmental Sciences |
| Aquatic ecotoxicology with emphasis on freshwater insects, mollusks and crustaceans; assessing anthropogenic impacts on benthic macroinvertebrate communities; trophic transfer of contaminants; effects of contaminants on invertebrate bioenergetics; impacts of coal-associated contaminants; invasive species. |
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Matthew A. Wallig
Departments of Pathobiology and Nutritional Sciences |
| Biological effects of phytochemicals that influence toxicity and cancer development; nutritional toxicology, toxicologic pathology. |
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